EMPIAR-11823 - Cryo-EM of the human CAK: Data for 1.73 Å-resolution reconstruction [multiple data sets in EER format]

EMPIAR-11823

Cryo-EM of the human CAK: Data for 1.73 Å-resolution reconstruction [multiple data sets in EER format]

Publication:

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barrett AGM, Ali S, Kotecha A, Greber BJ

Nature communications 15 (2024)

PMID: 38480681

DOI: 10.1038/s41467-024-46375-9

Related EMDB entry:

EMD-17522

Deposited:

2023-12-05

Released:

2024-05-20

Last modified:

2024-05-20

Imageset size:

12.13 TB

Imageset DOI:

10.6019/EMPIAR-11823

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. EER movies, CAK-ICEC0943, grid VC1-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5729

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220312_VC1-1/).

Files:

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2. EER movies, CAK-ICEC0768, grid VC2-4

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5583

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220312_VC2-4/).

Files:

This entry cannot be downloaded from PDBj.

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Download a list of selected files.

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3. EER movies, CAK-dinaciclib, grid VC4-3

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5210

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220128_ICR_VC4-3/).

Files:

This entry cannot be downloaded from PDBj.

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Download a list of selected files.

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rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

4. EER movies, CAK-BS181, grid VC8-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5203

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220311_VC8-1/).

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

5. EER movies, CAK-ICEC0942, grid VC13-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5231

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220129_VC13-3/). This dataset was only used for the high-resolution (1.73 Å) reconstruction, not for interpretation of inhibitor interactions described in the manuscript.

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

6. EER movies, CAK-ICEC0942, grid VC14-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5367

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/Krios3_220409_ICR_VC14-1/). This dataset was used both for the high-resolution (1.73 Å) reconstruction and for interpretation of inhibitor interactions described in the manuscript.

Files:

This entry cannot be downloaded from PDBj.

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