EMPIAR-11717
CryoEM movies of IAPP-S20G timecourse (22 week, FT14) [4373 multi-frame micrographs composed of 40 frames each in TIFF format]
Publication:

Structural evolution of fibril polymorphs during amyloid assembly

Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA

Cell 186 (2023) 5798-5811.e26

PMID: 38134875

Related EMDB entry:
Deposited:
2023-08-03
Released:
2024-04-17
Last modified:
2024-04-17
Imageset size:
602.02 GB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned tif movie stacks (gain corrected) for the IAPP-S20G 22 week cryoEM dataset
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
4373
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.9, 0.9)
Details:
Only unaligned movies are present. The total dose was 39 e-/Å2 over 40 frames. Only half the movies were processed for the paper, a total of four fibril polymorphs were identified, with four structures resolved (2PFl, 4PFcu, 4PFlu & 4PFlj).
Files:
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Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)