EMPIAR-11401 - PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S - RyR2-R2474S [10671 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11401

PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S - RyR2-R2474S [10671 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment

Miotto MC, Weninger G, Dridi H, Yuan Q, Liu Y, Wronska A, Melville Z, Sittenfeld L, Reiken S, Marks AR

Science advances 8 (2022)

PMID: 35857850

DOI: 10.1126/sciadv.abo1272

Related EMDB entry:

EMD-26410 EMD-26409

Deposited:

2023-01-30

Released:

2023-02-08

Last modified:

2023-02-08

Imageset size:

2.35 TB

Imageset DOI:

10.6019/EMPIAR-11401

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S - RyR2-R2474S

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10671

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.83, 0.83)

Details:

Reference: references/21jul14a_14114053_01_4092x5760_norm_0.mrc (must invert in Y).

Files:

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Citations

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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