EMPIAR-11326 - Single particle cryo-EM structure of RIG-I in complex with p3dsRNA [3480 multi-frame micrographs composed of 34 frames each in TIFF format]

EMPIAR-11326

Single particle cryo-EM structure of RIG-I in complex with p3dsRNA [3480 multi-frame micrographs composed of 34 frames each in TIFF format]

Publication:

The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands

Wang W, Pyle AM

Molecular cell 82 (2022) 4131-4144.e6

PMID: 36272408

DOI: 10.1016/j.molcel.2022.09.029

Related EMDB entry:

EMD-26022

Deposited:

2022-11-01

Released:

2022-12-06

Last modified:

2022-12-06

Imageset size:

1020.25 GB

Imageset DOI:

10.6019/EMPIAR-11326

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of RIG-I in complex with p3dsRNA

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3480

Image size:

(7676, 7420)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.525, 0.525)

Details:

The micrographs are the average, without any realignment, of 34 raw movie frames (accumulating 61 electron per squared Angstrom in a 8.5 second exposure).

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Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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