EMPIAR-11033 - cryoEM structure of Go-coupled 5-HT5A with agonist 5-CT [4006 micrographs in MRC format]

EMPIAR-11033

cryoEM structure of Go-coupled 5-HT5A with agonist 5-CT [4006 micrographs in MRC format]

Publication:

Inactive and active state structures template selective tools for the human 5-HT_5A receptor

Zhang S, Chen H, Zhang C, Yang Y, Popov P, Liu J, Krumm BE, Cao C, Kim K, Xiong Y, Katritch V, Shoichet BK, Jin J, Fay JF, Roth BL

Nature structural & molecular biology 29 (2022) 677-687

PMID: 35835867

DOI: 10.1038/s41594-022-00796-6

Related EMDB entry:

EMD-26597

Deposited:

2022-04-27

Released:

2022-07-27

Last modified:

2022-07-27

Imageset size:

351.75 GB

Imageset DOI:

10.6019/EMPIAR-11033

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Aligned multi-frame micrographs

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

4006

Image size:

(5760, 4092)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.91, 0.91)

Details:

The micrographs are dose weighted motion corrected with a total electron exposure of 29.07 e/A2

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Citations

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Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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