EMPIAR-10803 - Cryo-electron microscopy reconstruction of ATP-bound human P-glycoprotein [5986 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-10803

Cryo-electron microscopy reconstruction of ATP-bound human P-glycoprotein [5986 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Kim Y, Chen J

Science (New York, N.Y.) 359 (2018) 915-919

PMID: 29371429

DOI: 10.1126/science.aar7389

Related EMDB entry:

EMD-7325

Deposited:

2021-09-10

Released:

2021-11-16

Last modified:

2021-11-16

Imageset size:

2.15 TB

Imageset DOI:

10.6019/EMPIAR-10803

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned and uncorrected multiframe movies of human ATP-bound P-glycoprotein

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

5986

Image size:

(7420, 7676)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.42, 0.42)

Details:

Unaligned and uncorrected multiframe movies of human ATP-bound P-glycoprotein. The super-resolution pixel size is 0.42 Angstrom (0.84 Angstrom after binning). The movies are separated into two subdirectories each with their own gain reference.

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

Krentzel D, Elphick M, Domart MC, Peddie CJ, Laine RF, Shand C, Henriques R, Collinson LM, Jones ML. (2025)

CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

Arora S, Pan SH, Kumar S, Singh SK, Chauhan U, Alhalabi W, Arya V, Alsulami BS, Hsu CH, Chui KT, Gupta BB. (2025)

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning.

Costa-Gomes B, Greer J, Juraschko N, Parkhurst J, Mirecka J, Famili M, Rangel-Smith C, Strickson O, Lowe A, Basham M, Burnley T. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

EMICSS: added-value annotations for EMDB entries.

Duraisamy AK, Fonseca N, Kleywegt GJ, Patwardhan A, Morris KL. (2025)

Global conformations of <i>Pichia pastoris</i> complex I are distinguished by the binding of a unique interdomain bridging subunit.

Lee CS, Grba DN, Wright JJ, Ivanov BS, Hirst J. (2025)

Overcoming Preferred Orientation in Cryo-EM With Ultrasonic Excitation During Vitrification

Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ. (2025)

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