EMPIAR-12651
CryoEM structural characterization of α-Synuclein Oligomer [stack of 2528 particles in MRCS format]
Publication:

A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion

Santos J, Cuellar J, Pallarès I, Byrd EJ, Lends A, Moro F, Abdul-Shukkoor MB, Pujols J, Velasco-Carneros L, Sobott F, Otzen DE, Calabrese AN, Muga A, Pedersen JS, Loquet A, Valpuesta JM, Radford SE, Ventura S

Journal of the American Chemical Society 146 (2024) 12702-12711

PMID: 38683963

Related EMDB entry:
Deposited:
2025-03-26
Released:
2025-03-31
Last modified:
2025-03-31
Imageset size:
37.33 GB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • picked particles - multiframe - processed
1. Particles of a-synuclein
Category:
picked particles - multiframe - processed
Image format:
MRCS
No. of images or tilt series:
2528
Image size:
(80, 80)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(2.74, 2.74)
Details:
the original images pixel size was 1.37. These are 2x binned particles.
Files:
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Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)