EMPIAR-11812 - Structure of 4R2N ClearTau [25793 multi-frame micrographs composed of 1150 frames each in EER format]

EMPIAR-11812

Structure of 4R2N ClearTau [25793 multi-frame micrographs composed of 1150 frames each in EER format]

Publication:

Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates

Limorenko G, Tatli M, Kolla R, Nazarov S, Weil MT, Schöndorf DC, Geist D, Reinhardt P, Ehrnhoefer DE, Stahlberg H, Gasparini L, Lashuel HA

Nature communications 14 (2023)

PMID: 37402718

DOI: 10.1038/s41467-023-39314-7

Related EMDB entry:

EMD-18874

Deposited:

2023-11-29

Released:

2025-02-04

Last modified:

2025-02-04

Imageset size:

8.38 TB

Imageset DOI:

10.6019/EMPIAR-11812

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of ClearTau 4R2N isoform

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

25793

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.726, 0.726)

Details:

EER-format movie files are within sub-folders under the "Images-Disc1" directory. The gain reference image is in the data folder. Raw micrographs, not motion-corrected.

Files:

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Citations

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Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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