EMPIAR-11475 - Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2 [18846 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-11475

Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2 [18846 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, Kuriyan J, Vapalahti O, Balistreri G, Kirchhausen T, Brunger AT

Proceedings of the National Academy of Sciences of the United States of America 119 (2022)

PMID: 36122200

DOI: 10.1073/pnas.2210990119

Related EMDB entry:

EMD-27098

Deposited:

2023-03-22

Released:

2023-04-13

Last modified:

2023-04-13

Imageset size:

4.62 TB

Imageset DOI:

10.6019/EMPIAR-11475

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of the scaffolded HR1HR2 complex with extended HR2

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

18846

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.3265, 0.3265)

Details:

Please refer to the published paper for details.

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

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Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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