EMPIAR-11303 - Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG [2651 multi-frame micrographs composed of 48 frames each in TIFF format]

EMPIAR-11303

Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG [2651 multi-frame micrographs composed of 48 frames each in TIFF format]

Publication:

Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro

Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Diskson DW, Vinters HV, Eisenberg DS

Nature Communications 13 (2022) 1-12

PMID: 36114178

DOI: 10.1038/s41467-022-32951-4

Related EMDB entry:

EMD-26663

Deposited:

2022-11-10

Released:

2022-11-21

Last modified:

2022-11-21

Imageset size:

2.49 TB

Imageset DOI:

10.6019/EMPIAR-11303

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame movies

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

2651

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.539, 0.539)

Details:

Dosage is 1.66 e/A^2. Gain and Dark corrected frames.

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Citations

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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