EMPIAR-11176 - human ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.4/5 Spike [7254 multi-frame micrographs composed of 1092 frames each in EER format]

EMPIAR-11176

human ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.4/5 Spike [7254 multi-frame micrographs composed of 1092 frames each in EER format]

Publication:

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

Ni D, Turelli P, Beckert B, Nazarov S, Uchikawa E, Myasnikov A, Pojer F, Trono D, Stahlberg H, Lau K

(---)

DOI: 10.1371/journal.ppat.1011206

Related EMDB entry:

EMD-15588 EMD-15587

Deposited:

2022-08-23

Released:

2023-03-30

Last modified:

2023-03-30

Imageset size:

4.15 TB

Imageset DOI:

10.6019/EMPIAR-11176

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. human ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.4/5 Spike

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

7254

Image size:

(4096, 4096)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(0.83, 0.83)

Details:

raw micrographs collected on Falcon 4

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Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

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