EMPIAR-10673 - Cryo-EM of GLP-1 receptor bound to GLP-1 and Gs protein [5739 multi-frame micrographs composed of 75 frames each in TIFF format]

EMPIAR-10673

Cryo-EM of GLP-1 receptor bound to GLP-1 and Gs protein [5739 multi-frame micrographs composed of 75 frames each in TIFF format]

Publication:

Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D

Molecular cell 80 (2020) 485-500.e7

PMID: 33027691

DOI: 10.1016/j.molcel.2020.09.020

Related EMDB entry:

EMD-21992

Deposited:

2021-03-22

Released:

2021-06-04

Last modified:

2021-06-04

Imageset size:

1.88 TB

Imageset DOI:

10.6019/EMPIAR-10673

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Non-gain-normalized LZW-TIFF compressed movies of GLP-1R-GLP-1 in a detergent micelle

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

5739

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.83, 0.83)

Details:

The "Dataset_details_GLP-1R-GLP-1.txt" file contains details about the experiment and the dataset. The gain reference created from the dataset is "GLP-1_gain.mrc". The particles from the last 3D auto-refinement are in the file "GLP-1_data.star".

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Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

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