EMPIAR-10662 - SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs [3576 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-10662

SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs [3576 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Small molecule SWELL1-LRRC8 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

Gunasekar SK, Xie L, Chheda PR, Kang C, Kern DM, My-Ta C, Kumar A, Maurer J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Kulkarni CA, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Brohawn SG, Kerns R, Sah R

bioRxiv (2021)

DOI: 10.1101/2021.02.28.432901

Related EMDB entry:

EMD-23614

Deposited:

2021-01-21

Released:

2021-04-14

Last modified:

2021-04-14

Imageset size:

2.71 TB

Imageset DOI:

10.6019/EMPIAR-10662

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. LRRC8A-SN-407 in MSP1E3D1 nanodiscs

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3576

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.5685, 0.5685)

Details:

Gain reference is included in the "SN407_frames" folder with the movies. Dose per frame= 1.0318 e/A2. The SN407_particles folder contains both the whole set of polished particles and two Refine3D data files (pointing to a classed set of polished particles) for the SN-407 poses.

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Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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