EMPIAR-11823
Cryo-EM of the human CAK: Data for 1.73 Å-resolution reconstruction [multiple data sets in EER format]
Publication:

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barrett AGM, Ali S, Kotecha A, Greber BJ

Nature communications 15 (2024)

PMID: 38480681

Related EMDB entry:
Deposited:
2023-12-05
Released:
2024-05-20
Last modified:
2024-05-20
Imageset size:
12.13 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. EER movies, CAK-ICEC0943, grid VC1-1
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5729
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220312_VC1-1/).
Files:
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2. EER movies, CAK-ICEC0768, grid VC2-4
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5583
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220312_VC2-4/).
Files:
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3. EER movies, CAK-dinaciclib, grid VC4-3
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5210
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220128_ICR_VC4-3/).
Files:
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4. EER movies, CAK-BS181, grid VC8-1
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5203
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220311_VC8-1/).
Files:
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5. EER movies, CAK-ICEC0942, grid VC13-1
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5231
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220129_VC13-3/). This dataset was only used for the high-resolution (1.73 Å) reconstruction, not for interpretation of inhibitor interactions described in the manuscript.
Files:
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6. EER movies, CAK-ICEC0942, grid VC14-1
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
5367
Image size:
(4096, 4096)
Pixel type:
BIT
Pixel spacing:
(0.57, 0.57)
Details:
EER movies. The gain reference can be found in the top directory (data/Krios3_220409_ICR_VC14-1/). This dataset was used both for the high-resolution (1.73 Å) reconstruction and for interpretation of inhibitor interactions described in the manuscript.
Files:
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Files:
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