EMPIAR-10925
C-terminal half of LRRK2 (I2020T) bound to microtubule in presence of MLi-2 kinase inhibitor [2354 multi-frame micrographs composed of 55 frames each in TIFF format]
Publication:

Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules

Snead DM, Matyszewski M, Dickey AM, Lin YX, Leschziner AE, Reck-Peterson SL

Nature structural & molecular biology 29 (2022) 1196-1207

PMID: 36510024

Deposited:
2021-09-21
Released:
2023-01-03
Last modified:
2023-01-03
Imageset size:
684.82 GB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of microtubule bound C-terminus of LRRK2 (I2020T) with MLi-2 kinase inhibitor present
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
2354
Image size:
(3710, 3838)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(1.16, 1.16)
Details:
Contains data collected from 2 grids (20sep10b and 20sep30c) made on the same day with same conditions. Each folder contains its own gain reference with the "_norm.mrc" suffix found in the references folder. Blank dark references are also included but are not needed for correction. Gain correction in cryosparc should work with default settings, while for motioncor2, please flip the image and apply no rotation.
Files:
Loading...
Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)