EMPIAR-10917
Single particle cryo-EM dataset of sarkosyl-insoluble fraction from the frontal cortex of an individual with pathological aging of amyloid-β 42 filaments [1189 multi-frame micrographs composed of 48 frames each in TIFF format]
Publication:

Cryo-EM structures of amyloid-β 42 filaments from human brains

Yang Y, Arseni D, Zhang WJ, Huang M, Lovestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew S, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Falcon B, Scheres SHW, Goedert M

Science (New York, N.Y.) 375 (2022) 167-172

PMID: 35025654

Related EMDB entry:
Deposited:
2022-01-06
Released:
2022-01-24
Last modified:
2023-01-23
Imageset size:
1.11 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame movies
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1189
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.73, 0.73)
Details:
The files were written as tiff files by EPU. The pixel size is 0.73 A/px. The dose rate is 1 e/A2/frame. Please use gain-reference.mrc as a gain reference without any rotation or flipping.
pick_coordinates contains start-end coordinates of the manually picked filaments.
Refine102_run_data.star contains STAR file(s) with the metadata of the final refined segments.
Files:
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