EMPIAR-10650
PKM2 in complex with Compound 6 [590 multi-frame micrographs composed of 75 frames each in TIFF format]
Publication:

Fragment-based drug discovery using cryo-EM

Saur M, Hartshorn MJ, Dong J, Reeks J, Bunkoczi G, Jhoti H, Williams PA

Drug discovery today (2019)

PMID: 31877353

Related EMDB entry:
Deposited:
2021-02-23
Released:
2021-03-12
Last modified:
2021-03-12
Imageset size:
767.96 GB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Data from EPU (movies have been converted to compressed TIF)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
590
Image size:
(4096, 4096)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(0.68, 0.68)
Details:
This dataset provides the 'Data' folder inside Images-Disc1/GridSquare..../ folders. The movies have been converted to compressed TIF files to safe space using relion_convert_to_tiff. Standard values have been used for conversion, i.e. compression is zip level 6.
Files:
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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)