EMPIAR-10786 - Cryo electron microscopy final particle stacks of Substance P-Neurokinin Receptor G protein complexes [multiple data sets in MRCS format]

EMPIAR-10786

Cryo electron microscopy final particle stacks of Substance P-Neurokinin Receptor G protein complexes [multiple data sets in MRCS format]

Publication:

Selective G protein signaling driven by substance P-neurokinin receptor dynamics

Harris JA, Faust B, Gondin AB, Dämgen MA, Suomivuori CM, Veldhuis NA, Cheng Y, Dror RO, Thal DM, Manglik A

Nature chemical biology 18 (2021) 109-115

PMID: 34711980

DOI: 10.1038/s41589-021-00890-8

Related EMDB entry:

EMD-24569 EMD-24570 EMD-24572

Deposited:

2021-07-27

Released:

2022-07-26

Last modified:

2022-07-26

Imageset size:

170.84 GB

Imageset DOI:

10.6019/EMPIAR-10786

Experimental metadata:

Download xml json

Contains:

picked particles - single frame - processed

Image Sets

1. Particle stack and final .star file for SP-NK1R-miniGs399 reconstruction

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

288659

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.86, 0.86)

Details:

This directory contains the final particle stack and .star file containing shifts/poses for the published SP-NK1R-miniGs399 reconstruction.

Files:

Archives and downloads the selected files into an uncompressed zip file.

Depending on the number and size of files to be downloaded, this can take an enormous amount of time. Also, this feature is unstable and may not work properly, and checksums of downloaded files are not verified.

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Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

2. Particle stack and final .star file for SP6-11-NK1R-miniGsq70 reconstruction

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

59926

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.835, 0.835)

Details:

This directory contains the final particle stack and .star file containing shifts/poses for the published SP6-11-NK1R-miniGsq70 reconstruction.

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

3. Particle stack and final .star file for SP-NK1R-miniGsq70 reconstruction

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

122220

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.835, 0.835)

Details:

This directory contains the final particle stack and .star file containing shifts/poses for the published SP-NK1R-miniGsq70 reconstruction.

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

Browse All Files

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

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Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

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