EMPIAR-10247 - TRPV2 ion channel gating through allosteric domain coupling revealed by cryo-EM [1969 multi-frame micrographs composed of 35 frames each in MRCS format]

EMPIAR-10247

TRPV2 ion channel gating through allosteric domain coupling revealed by cryo-EM [1969 multi-frame micrographs composed of 35 frames each in MRCS format]

Publication:

Structures of TRPV2 in distinct conformations provide insight into role of the pore turret

Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W

Nature structural & molecular biology 26 (2018) 40-49

PMID: 30598551

DOI: 10.1038/s41594-018-0168-8

Related EMDB entry:

EMD-7118

Deposited:

2019-01-07

Released:

2019-07-25

Last modified:

2019-07-25

Imageset size:

3.93 TB

Imageset DOI:

10.6019/EMPIAR-10247

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. TRPV2 WT with pore turret domain

Category:

micrographs - multiframe

Image format:

MRCS

No. of images or tilt series:

1969

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

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Citations

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

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CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

Arora S, Pan SH, Kumar S, Singh SK, Chauhan U, Alhalabi W, Arya V, Alsulami BS, Hsu CH, Chui KT, Gupta BB. (2025)

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning.

Costa-Gomes B, Greer J, Juraschko N, Parkhurst J, Mirecka J, Famili M, Rangel-Smith C, Strickson O, Lowe A, Basham M, Burnley T. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

In situ structure determination of conformationally flexible targets using nextPYP.

Liu HF, Zhou Y, Huang Q, Martin J, Bartesaghi A. (2025)

EMICSS: added-value annotations for EMDB entries.

Duraisamy AK, Fonseca N, Kleywegt GJ, Patwardhan A, Morris KL. (2025)

Global conformations of <i>Pichia pastoris</i> complex I are distinguished by the binding of a unique interdomain bridging subunit.

Lee CS, Grba DN, Wright JJ, Ivanov BS, Hirst J. (2025)

Overcoming Preferred Orientation in Cryo-EM With Ultrasonic Excitation During Vitrification

Williams HM, Curtis WA, Haubner M, Hruby J, Drabbels M, Lorenz UJ. (2025)

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