EMPIAR-10199 - Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses [2120 micrographs in MRC format]

EMPIAR-10199

Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses [2120 micrographs in MRC format]

Publication:

A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses

Abdelnabi R, Geraets JA, Ma Y, Mirabelli C, Flatt JW, Domanska A, Delang L, Jochmans D, Kumar TA, Jayaprakash V, Sinha BN, Leyssen P, Butcher SJ, Neyts J

PLoS biology 17 (2019)

PMID: 31185007

DOI: 10.1371/journal.pbio.3000281

Related EMDB entry:

EMD-0103

Deposited:

2018-07-12

Released:

2019-08-07

Last modified:

2021-09-01

Imageset size:

2.20 TB

Imageset DOI:

10.6019/EMPIAR-10199

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Unaligned multi-frame micrographs of CVB3 in complex with a small molecular inhibitor

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

2120

Image size:

(3838, 3710)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(1.048, 1.048)

Details:

These data are unaligned frames (20 dose fractions) collected on a K2 Summit in counting mode at Diamond Light Source, U.K. Total electron dose was ~47e-/Å². Micrographs are grouped by the GridSquare in which they were collected. Also included are the particle coordinates for 10173 particles after 2D classification (Relion particle coordinate STAR file format).

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