EMPIAR-12676 - Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982 [508 multi-frame micrographs composed of 2030 frames each in EER format]

EMPIAR-12676

Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982 [508 multi-frame micrographs composed of 2030 frames each in EER format]

Publication:

Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination

Kim D, Liu W, Viner R, Cherezov V

Structure (London, England : 1993) 32 (2024) 2206-2219.e4

PMID: 39471802

DOI: 10.1016/j.str.2024.10.004

Related EMDB entry:

EMD-43236

Deposited:

2025-04-02

Released:

2025-07-25

Last modified:

2025-07-25

Imageset size:

490.49 GB

Imageset DOI:

10.6019/EMPIAR-12676

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Multiframe EER format files of GPR119-MBX-2982-Gs-Nb35 complex on Glacios

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

508

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.92, 0.92)

Details:

---

Files:

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

See all citations

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