EMPIAR-12518 - Single particle analysis datasets of in vitro grown aSyn filaments [multiple data sets in MRC format]

EMPIAR-12518

Single particle analysis datasets of in vitro grown aSyn filaments [multiple data sets in MRC format]

Publication:

A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features.

Brücke C, Al-Azzani M, Ramalingam N, Ramón M, Sousa RL, Buratti F, Zech M, Sicking K, Amaral L, Gelpi E, Chandran A, Agarwal A, Chaves S, Fernández CO, Dettmer U, Lautenschläger J, Zweckstetter M, Fernandez-Busnadiego R, Zimprich A, Outeiro TF

(---)

PMID: 39399048

DOI: 10.1101/2024.09.23.24313864.

Related EMDB entry:

EMD-52165

Deposited:

2025-01-06

Released:

2025-02-10

Last modified:

2025-02-10

Imageset size:

1023.52 GB

Imageset DOI:

10.6019/EMPIAR-12518

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Dataset containing WT aSyn TEM micrographs

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

4093

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.92, 0.92)

Details:

---

Files:

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2. Dataset containing aSyn G14R TEM micrographs

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

6475

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.92, 0.92)

Details:

---

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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3. Dataset containing aSyn K58N TEM micrographs

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

5811

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.92, 0.92)

Details:

---

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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