EMPIAR-12254 - Full-length mouse 5-HT3A receptor in complex with ALB148471, pre-activated and open-like [6312 multi-frame micrographs composed of 55 frames each in TIFF format]

EMPIAR-12254

Full-length mouse 5-HT3A receptor in complex with ALB148471, pre-activated and open-like [6312 multi-frame micrographs composed of 55 frames each in TIFF format]

Publication:

Structural basis for partial agonism in 5-HT_3A receptors

Felt K, Stauffer M, Salas-Estrada L, Guzzo PR, Xie D, Huang J, Filizola M, Chakrapani S

Nature structural & molecular biology 31 (2024) 598-609

PMID: 38177669

DOI: 10.1038/s41594-023-01140-2

Related EMDB entry:

EMD-29422 EMD-29409

Deposited:

2024-08-29

Released:

2024-10-08

Last modified:

2024-10-08

Imageset size:

3.88 TB

Imageset DOI:

10.6019/EMPIAR-12254

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Raw movies, 5-HT3A + ALB148471

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

6312

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.1, 1.1)

Details:

Raw movies of 5-HT3AR in complex with 3x molar excess ALB148471. Collected on titan krios and k3 camera. 81,000x magnification, super-resolution (import with 0.55 angstrom pixel size, 2x bin in Motioncorr), around 1 electron dose per frame. Dataset 1 of 2.

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Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

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