EMPIAR-11928
Cryo electron structure of the ectodomain of SPRING bound to the ectodomain of Site-one protease [4886 multi-frame micrographs composed of 50 frames each in TIFF format]
Publication:

SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain

Hendrix S, Dartigue V, Hall H, Bawaria S, Kingma J, Bajaj B, Zelcer N, Kober DL

Nature communications 15 (2024)

PMID: 38977690

Related EMDB entry:
Deposited:
2023-11-07
Released:
2025-03-17
Last modified:
2025-03-17
Imageset size:
2.93 TB
Imageset DOI:
Experimental metadata:
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Contains:
  • micrographs - multiframe
1. K3 movies for site-one protease complexed to SPRING
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
4886
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(1.08, 1.08)
Details:
Unprocessed movies collected on Titan Krios G2 using bioquantum K3 operating in CDS mode. Superres pixel size is 0.54 A. Collected with a dose rate of 8 eps with a total dose of 48 e/A2. Nominal defocus range of -1 to -2 micron. Data are related to EMD-42639.
Files:
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