EMPIAR-11093 - Micrographs of IAPP (amylin) amyloid fibrils [1330 micrographs in MRC format]

EMPIAR-11093

Micrographs of IAPP (amylin) amyloid fibrils [1330 micrographs in MRC format]

Publication:

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

Röder C, Kupreichyk T, Gremer L, Schäfer LU, Pothula KR, Ravelli RBG, Willbold D, Hoyer W, Schröder GF

Nature structural & molecular biology 27 (2020) 660-667

PMID: 32541895

DOI: 10.1038/s41594-020-0442-4

Related EMDB entry:

EMD-10669 EMD-10671 EMD-10670

Deposited:

2020-09-11

Released:

2022-07-27

Last modified:

2022-07-27

Imageset size:

83.13 GB

Imageset DOI:

10.6019/EMPIAR-11093

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. MotionCor2-aligned single frame of islet amyloid polypeptide fibrils

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

1330

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.935, 0.935)

Details:

These data are aligned average micrographs collected on a Technai Arctica at 200kV with a Falcon III detector operating in electron counting mode. Applied defocus values ranged from −1 to −2.2 µm. MotionCor2 was used to align 50 dose fractions that were taken with a total electron dose of ~42e-/Å².

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Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

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