EMPIAR-10912 - Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha1, beta3 and gamma subunits, in presence of Ro15-4513 and megabody Mb38 [689 multi-frame micrographs composed of 65 frames each in MRC format]

EMPIAR-10912

Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha1, beta3 and gamma subunits, in presence of Ro15-4513 and megabody Mb38 [689 multi-frame micrographs composed of 65 frames each in MRC format]

Publication:

Differential assembly diversifies GABA_A receptor structures and signalling

Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR

Nature (2022)

PMID: 35355020

DOI: 10.1038/s41586-022-04517-3

Related EMDB entry:

EMD-14076

Deposited:

2021-12-29

Released:

2022-04-04

Last modified:

2022-04-04

Imageset size:

1.37 TB

Imageset DOI:

10.6019/EMPIAR-10912

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of GABA(A)Rs purified from cells expressing human full-length alpha1, beta3 and gamma subunits, in presence of Ro15-4513 and megabody Mb38

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

689

Image size:

(4096, 4096)

Pixel type:

SIGNED 16 BIT INTEGER

Pixel spacing:

(1.06, 1.06)

Details:

Falcon 3 movies with a total dose of 28 e/A2 collected with a Volta Phase Plate.

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Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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