EMPIAR-10632 - Cryo electron microscopy of alpha-synuclein H50Q fibrils [3577 multi-frame micrographs composed of 30 frames each in MRC format]

EMPIAR-10632

Cryo electron microscopy of alpha-synuclein H50Q fibrils [3577 multi-frame micrographs composed of 30 frames each in MRC format]

Publication:

Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs

Boyer DR, Li B, Sun C, Fan W, Sawaya MR, Jiang L, Eisenberg DS

Nature structural & molecular biology 26 (2019) 1044-1052

PMID: 31695184

DOI: 10.1038/s41594-019-0322-y

Related EMDB entry:

EMD-20328

Deposited:

2021-01-26

Released:

2021-03-03

Last modified:

2021-03-03

Imageset size:

595.30 GB

Imageset DOI:

10.6019/EMPIAR-10632

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned K2 movies of alpha-synuclein H50Q fibrils

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

3577

Image size:

(3838, 3710)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(1.07, 1.07)

Details:

Movies are unaligned. 30 frames. Gain image does not need to be flipped. Grouped movies into two groups, first 2533 images had average dose of ~4.8 e/A^2/s, last 1024 images had dose of 3.2 e/A^2/s.

Files:

Archives and downloads the selected files into an uncompressed zip file.

Depending on the number and size of files to be downloaded, this can take an enormous amount of time. Also, this feature is unstable and may not work properly, and checksums of downloaded files are not verified.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

Browse All Files

Quick Links

Talks and Tutorials

EMPIAR Quick tour

Statistics

Publications

Re-use case study

EMPIAR in the news

Claim entries to your ORCiD

COVID-19 Data Portal

EMDB

PDBe

BioImage Archive

EMNavigator@PDBj

PDBj

RCSB@PDBj

EMDataResoruce@RCSB,EMDB,NCMI

Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

See all citations

Protein Data Bank Japan News

[2024-11-06]

404 new PDB entries have been released on 2024-11-06.

[2024-11-01]

A new portal integrating genome variants and protein structures has released

[2024-10-30]

[wwPDB] Deprecation of FTP File Download Protocol on November 1, 2024

[2024-10-25]

PDBj luncheon seminar at APBJC 2024

[2024-10-17]

[wwPDB] The Nobel Prize in Chemistry 2024