EMPIAR-10230 - Cryo electron microscopy of tau filaments from sporadic Alzheimer's disease brain [507 micrographs in MRC format]

EMPIAR-10230

Cryo electron microscopy of tau filaments from sporadic Alzheimer's disease brain [507 micrographs in MRC format]

Publication:

Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold

Falcon B, Zhang W, Schweighauser M, Murzin AG, Vidal R, Garringer HJ, Ghetti B, Scheres SHW, Goedert M

Acta neuropathologica 136 (2018) 699-708

PMID: 30276465

DOI: 10.1007/s00401-018-1914-z

Related EMDB entry:

EMD-0259

Deposited:

2018-10-17

Released:

2019-02-20

Last modified:

2021-08-06

Imageset size:

27.01 GB

Imageset DOI:

10.6019/EMPIAR-10230

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Dose-weighted micrographs of tau filaments from sporadic Alzheimer's disease brain (case 2)

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

507

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(1.15, 1.15)

Details:

Start- and end-points of filaments for PHFs and SFs written out as tube coordinate .star files with the following syntax (ignore comments after //):

data_

loop_
_rlnCoordinateX #1
_rlnCoordinateY #2
110.000000 1080.000000 // Tube 1 starting coordinates x, y
1855.000000 585.000000 // Tube 1 end coordinates x, y
635.000000 1325.000000 // Tube 2
560.000000 2490.000000
...

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