EMPIAR-11715
CryoEM movies of IAPP-S20G timecourse (6 week, FT11) [2350 multi-frame micrographs composed of 30 frames each in TIFF format]
Publication:

Structural evolution of fibril polymorphs during amyloid assembly

Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA

Cell 186 (2023) 5798-5811.e26

PMID: 38134875

Related EMDB entry:
Deposited:
2023-08-03
Released:
2024-04-17
Last modified:
2024-04-17
Imageset size:
316.15 GB
Imageset DOI:
Experimental metadata:
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Contains:
  • micrographs - multiframe
1. Unaligned tif movie stacks (gain corrected) for the IAPP-S20G 6 week cryoEM dataset
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
2350
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.84, 0.84)
Details:
Only unaligned movies are present. The total dose was 43 e-/Å2 over 30 frames. At least six fibril polymorphs were identified, with four structures resolved (2PFc, 2PFl, 3PFcu & 4PFcu).
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Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)
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