Release date Imageset Title Authors and references Size Resolution
2022-04-13
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Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation [4729 multi-frame micrographs composed of 40 frames each in MRC format] Abskharon R, Sawaya MR, Boyer DR, Cao Q, Nguyen BA, Cascio D, Eisenberg DS
[Pubmed: 35377792]
[DOI: 10.1073/pnas.2119952119]
693.4 GB 3.4 Å
2022-04-06
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CryoEM Structure of the, UND-PP bound, WaaL O-Antigen Ligase [2378 multi-frame micrographs composed of 50 frames each in MRC format] Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F
[Pubmed: 35388216]
[DOI: 10.1038/s41586-022-04555-x]
477.2 GB 3.23 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha4, beta3 and gamma2 subunits, in presence of GABA and nanobody Nb25 [14346 multi-frame micrographs composed of 48 frames each in TIFF format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
3.8 TB 3.0 - 3.1 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha4, beta3 and delta subunits, in presence of THIP (gaboxadol), histamine and nanobody Nb25 [6437 multi-frame micrographs composed of 48 frames each in TIFF format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
3.8 TB 2.9 - 3.4 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha4, beta3 and delta subunits, in presence of GABA, histamine, Ro15-4513 and nanobody Nb25 [10465 multi-frame micrographs composed of 48 frames each in TIFF format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
2.8 TB 2.9 - 3.0 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha1, beta3 and gamma subunits, in presence of Ro15-4513 and megabody Mb38 [689 multi-frame micrographs composed of 65 frames each in MRC format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
1.4 TB 2.7 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha4, beta3 and delta subunits, in presence of HEPES and nanobody Nb25 [18161 multi-frame micrographs composed of 32 frames each in TIFF format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
4.1 TB 2.5 - 2.9 Å
2022-04-04
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Cryo-EM micrographs of GABA(A)Rs purified from cells expressing human full-length alpha4, beta3 and delta subunits, in presence of GABA, histamine and nanobody Nb25 [11562 multi-frame micrographs composed of 48 frames each in TIFF format] Sente A, Desai R, Naydenova K, Malinauskas T, Jounaidi Y, Miehling J, Zhou X, Masiulis S, Hardwick SW, Chirgadze DY, Miller KW, Aricescu AR
[Pubmed: 35355020]
[DOI: 10.1038/s41586-022-04517-3]
3.0 TB 3.0 - 3.1 Å
2022-04-01
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2.3 A structure of the ATP-dependent chromatin remodeler Chd1 bound to the nucleosome in a nucleotide-free state [multiple data sets in TIFF, MRC and MRCS formats] Nodelman IM, Das S, Faustino AM, Fried SD, Bowman GD, Armache JP
[Pubmed: 35173352]
[DOI: 10.1038/s41594-021-00719-x]
4.7 TB 2.3 - 2.9 Å
2022-03-29
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Oxytocin receptor (OTR) bound to oxytocin in complex with a heterotrimeric Gq protein [7728 multi-frame micrographs composed of 50 frames each in TIFF format] Meyerowitz JG, Robertson MJ, Panova O, Skiniotis G
[Pubmed: 35241813]
[DOI: 10.1038/s41594-022-00728-4]
4.1 TB 2.9 Å
2022-03-28
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Single particle Cryo-EM data set for study the structural basis of Phosphatidylinositol 3-kinase type 2α (PI3KC2α) [multiple data sets in MRC format] Lo WT, Zhang Y, Vadas O, Roske Y, Gulluni F, De Santis MC, Zagar AV, Stephanowitz H, Hirsch E, Liu F, Daumke O, Kudryashev M, Haucke V
[Pubmed: 35256802]
[DOI: 10.1038/s41594-022-00730-w]
0.0 B 4.4 Å
2022-03-28
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Cryo-EM structure of SARS-CoV-2 Main protease C145S in complex with N-terminal peptide [multiple data sets in MRCS and TIFF formats] Godoy AS, Song Y, Noske GD, Oliva G 3.3 TB 3.5 Å
2022-03-28
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Representative data from Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of cytoplasmic vesicles and mitochondria during HSV-1 infection [14 reconstructed volumes in MRC format] Nahas KLN, Connor VC, Scherer KM, Kaminski CF, Harkiolaki M, Crump CM, Graham SC
[DOI: 10.1101/2021.10.11.463900]
9.9 GB
2022-03-22
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High-resolution Cryo-EM of Fab-labeled human parechovirus 3 [6759 multi-frame micrographs composed of 16 frames each in MRCS format] Domanska A, Flatt JW, Jukonen JJJ, Geraets JA, Butcher SJ
[Pubmed: 30463974]
[DOI: 10.1128/JVI.01597-18]
1.5 TB 2.8 Å
2022-03-21
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Structure of the GPCR dimer Ste2 bound to an antagonist [15751 multi-frame micrographs composed of 59 frames each in TIFF format] Velazhahan V, Tate CG
[Pubmed: 35296853]
[DOI: 10.1038/s41586-022-04498-3]
4.1 TB 2.7 Å
2022-03-21
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Structure of the ligand-free GPCR dimer Ste2 [9369 multi-frame micrographs composed of 53 frames each in EER format] Velazhahan V, Tate CG
[Pubmed: 35296853]
[DOI: 10.1038/s41586-022-04498-3]
8.2 TB 3.1 Å
2022-03-21
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Structure of the agonist-bound GPCR dimer Ste2 [6944 multi-frame micrographs composed of 50 frames each in MRC format] Velazhahan V, Tate CG
[Pubmed: 35296853]
[DOI: 10.1038/s41586-022-04498-3]
1.3 TB 3.46 - 3.53 Å
2022-03-21
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CryoEM of PreP prepared via Chameleon [multiple data sets in TIFF and MRC formats] Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
[Pubmed: 35383169]
[DOI: 10.1038/s41467-022-29322-4]
2.2 TB 3.3 - 4.6 Å
2022-03-21
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CryoEM Structure of mGlu2 - Gi Complex [45341 multi-frame micrographs composed of 50 frames each in TIFF format] Seven AB, Barros-Alvarez X, Skiniotis G
[Pubmed: 34194039]
[DOI: 10.1038/s41586-021-03680-3]
21.6 TB 3.2 Å
2022-03-21
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CryoET of E. coli prepared with the Waffle Method [1504 multi-frame micrographs composed of 14 frames each in TIFF format] Kelley K, Raczkowski AM, Klykov O, Jaroenlak P, Bobe D, Kopylov M, Eng ET, Bhabha G, Potter CS, Carragher B, Noble AJ
[Pubmed: 35387991]
[DOI: 10.1038/s41467-022-29501-3]
94.0 GB
2022-03-15
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Cryo-EM structure of human RNA polymerase I in elongation state [10053 multi-frame micrographs composed of 38 frames each in TIFF format] Misiaszek AD, Girbig M, Müller CW
[Pubmed: 34887565]
[DOI: 10.1038/s41594-021-00693-4]
3.6 TB 2.7 Å
2022-03-15
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Cryo-EM structure of human RNA polymerase I Open Complex and in complex with RRN3 [14224 multi-frame micrographs composed of 40 frames each in TIFF format] Misiaszek AD, Girbig M, Müller CW
[Pubmed: 34887565]
[DOI: 10.1038/s41594-021-00693-4]
2.2 TB 3.1 - 3.3 Å
2022-03-15
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CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495 [6613 multi-frame micrographs composed of 50 frames each in TIFF format] Seven AB, Barros-Alvarez X, Skiniotis G
[Pubmed: 34194039]
[DOI: 10.1038/s41586-021-03680-3]
3.2 TB 3.65 Å
2022-03-15
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CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate [7011 multi-frame micrographs composed of 50 frames each in TIFF format] Seven AB, Barros-Alvarez X, Skiniotis G
[Pubmed: 34194039]
[DOI: 10.1038/s41586-021-03680-3]
3.5 TB 3.3 Å
2022-03-15
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Seven benchmark datasets of instance segmentation of mitochondria: 6 diverse volume EM + 1 TEM (100 images) datasets [multiple data sets in TIFF format] Narayan K, Conrad RW
4.1 GB


Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)