EMPIAR-10664
Disease variant M854K MDA5-dsRNA filaments in complex with ADP-AlF4 [2177 multi-frame micrographs composed of 60 frames each in TIFF format]
Publication:

MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA

Yu Q, Herrero Del Valle A, Singh R, Modis Y

Nature communications 12 (2021)

PMID: 34795277

Related EMDB entry:
Deposited:
2021-03-07
Released:
2021-11-12
Last modified:
2022-02-25
Imageset size:
2.76 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of MDA5 variant M854K bound to dsRNA and ADP-ALF4
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
2177
Image size:
(4096, 4096)
Pixel type:
SIGNED 16 BIT INTEGER
Pixel spacing:
(1.084, 1.084)
Details:
Particle positions used for final reconstruction are in corresponding *particles.star files.
Each raw movie contain 60 unaligned frames (accumulating 29.6 electrons per square Å in a 60s exposure).
Files:
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