EMPIAR-11665
Atomic structure and conformational variability of the HER2-trastuzumab-pertuzumab complex [stack of 708609 particles in MRCS format]
Publication:

Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

Ruedas R, Vuillemot R, Tubiana T, Winter JM, Pieri L, Arteni AA, Samson C, Jonic S, Mathieu M, Bressanelli S

Journal of structural biology 216 (2024)

PMID: 38723875

Related EMDB entry:
Deposited:
2023-06-13
Released:
2024-06-13
Last modified:
2024-06-13
Imageset size:
207.20 GB
Imageset DOI:
Experimental metadata:
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Contains:
  • picked particles - multiframe - processed
1. Aligned particles images of the flexible HER2-Trastuzumab-Pertuzumab ternary complex
Category:
picked particles - multiframe - processed
Image format:
MRCS
No. of images or tilt series:
708609
Image size:
(280, 280)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(1.16, 1.16)
Details:
This the particle stack for the global reconstruction of the flexible HER2-Trastuzumab-Pertuzumab ternary complex. It allows reconstruction to an overall resolution < 3.3 A. The data sign is +1, white particle on dark background. The accompanying star file is exported from the last round of global refinement in cryoSPARC v. 4.1.2, with all the CTF parameters recorded. The dataset displays considerable continuous conformational variability.
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