The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2024-01-23 | Cryo electron microscopy micrographs of high molecular weight fractions from yeast native cell extracts [multiple data sets in MRC format] | Schmidt L, Tueting C, Kyrilis F, Hamdi F, Semchonok DA, Kastritis PL [DOI: 10.1101/2022.07.15.498668] |
4.7 TB | 3.78 - 8.1 Å | |
2018-09-10 | Cryo electron microscopy micrographs of yeast Exocyst complex [6472 multi-frame micrographs composed of 32 frames each in MRCS format] | Wang HW, Guo W, Li Y, Mei KR [Pubmed: 29335562] [DOI: 10.1038/s41594-017-0016-2] |
10.0 TB | 4.4 Å | |
2023-11-06 | Cryo electron microscopy movies of telithromycin bound to the Saccharomyces cerevisiae 80S ribosome (G2400A mutant). [4371 multi-frame micrographs composed of 30 frames each in MRCS format] | Koller TO, Wilson DN [Pubmed: 33990576] [DOI: 10.1038/s41467-021-23068-1] |
363.4 GB | 2.877 Å | |
2019-08-16 | Cryo electron microscopy of Cannabinoid Receptor 1-G Protein Complex [2756 multi-frame micrographs composed of 40 frames each in TIFF format] | Krishna Kumar K, Shalev-Benami M, Kobilka BK, Skiniotis G [Pubmed: 30639101] [DOI: 10.1016/j.cell.2018.11.040] |
476.0 GB | 3.0 Å | |
2023-04-13 | Cryo electron microscopy of DNA Polymerase alpha - primase bound to SARS-CoV-2 nsp1 virulence factor [2919 multi-frame micrographs composed of 48 frames each in TIFF format] | Kilkenny ML, Pellegrini L [Pubmed: 34719824] [DOI: 10.1002/pro.4220] |
751.3 GB | 4.12 - 4.4 Å | |
2023-06-05 | Cryo electron microscopy of Mce1 transporter from Mycobacterium smegmatis [multiple data sets in TIFF format] | Chen J, Bhabha G, Ekiert D [Pubmed: 37495693] [DOI: 10.1038/s41586-023-06366-0] |
20.9 TB | 2.71 - 3.19 Å | |
2020-11-13 | Cryo electron microscopy of RagAB from P. gingivalis solubilised in DDM [3635 multi-frame micrographs composed of 48 frames each in MRC format] | White JBR [Pubmed: 32393857] [DOI: 10.1038/s41564-020-0716-y] |
1.0 TB | 3.3 - 3.4 Å | |
2020-07-30 | Cryo electron microscopy of RyR1 in the presence and abscence of Ca, Caffeine and ATP ligands [stack of 791956 particles in SPIDER format] | Dashti A [Pubmed: 32948759] [DOI: 10.1038/s41467-020-18403-x] |
334.2 GB | 4.5 Å | |
2020-10-12 | Cryo electron microscopy of SARS-CoV-2 spike in prefusion state [3207 multi-frame micrographs composed of 30 frames each in MRC format] | Carazo JM [Pubmed: 33063791] [DOI: 10.1107/S2052252520012725] |
2.1 TB | 3.0 - 3.3 Å | |
2020-09-28 | Cryo electron microscopy of SARS-CoV-2 stabilized spike in prefusion state [3511 multi-frame micrographs composed of 40 frames each in TIFF format] | Carazo JM [Pubmed: 33063791] [DOI: 10.1107/S2052252520012725] |
865.0 GB | 2.9 Å | |
2019-10-17 | Cryo electron microscopy of TssA protein from T6SS of Vibrio cholerae. [multiple data sets in MRC and MRCS formats] | Nazarov S, Adaixo R, Basler M [Pubmed: 31403721] [DOI: 10.15252/embj.2018100825] |
1.3 TB | 3.9 Å | |
2024-02-13 | Cryo electron microscopy of Virus-like Particle based on PVY coat protein [502 multi-frame micrographs composed of 40 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
379.4 GB | 2.99 - 3.34 Å | |
2024-02-13 | Cryo electron microscopy of Virus-like Particle based on PVY coat protein with T43C and D136C mutation [461 multi-frame micrographs composed of 38 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
332.6 GB | 2.41 Å | |
2024-03-26 | Cryo electron microscopy of Virus-like Particle based on PVY coat protein with dC40 deletion [6215 multi-frame micrographs composed of 40 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
5.8 TB | 3.09 - 3.5 Å | |
2024-02-13 | Cryo electron microscopy of Virus-like Particle based on PVY coat protein with dC79 deletion [491 multi-frame micrographs composed of 41 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
377.4 GB | 3.2 Å | |
2015-08-28 | Cryo electron microscopy of YnaI [multiple data sets in MRC format] | Bottcher B, Prazak V, Rasmussen A, Black SS, Rasmussen T [Pubmed: 26256535] [DOI: 10.1016/j.str.2015.06.023] |
107.6 GB | 12.6 Å | |
2021-03-03 | Cryo electron microscopy of alpha-synuclein H50Q fibrils [3577 multi-frame micrographs composed of 30 frames each in MRC format] | Boyer DR, Li B, Sun C, Fan W, Sawaya MR, Jiang L, Eisenberg DS [Pubmed: 31695184] [DOI: 10.1038/s41594-019-0322-y] |
595.3 GB | 3.3 Å | |
2024-03-26 | Cryo electron microscopy of assemblies based on truncated PVY coat protein [2862 multi-frame micrographs composed of 44 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
2.3 TB | 2.93 - 3.62 Å | |
2024-02-29 | Cryo electron microscopy of assemblies based on truncated PVY coat protein with K176C mutation [9480 multi-frame micrographs composed of 32 frames each in TIFF format] | Kavcic L, Kezar A [Pubmed: 38233506] [DOI: 10.1038/s42004-024-01100-x] |
957.1 GB | 2.99 - 3.16 Å | |
2023-03-27 | Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant D76N (in vitro, pH 6.2) [3849 multi-frame micrographs composed of 36 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] |
575.5 GB | 3.0 - 4.1 Å | |
2023-03-27 | Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant V27M (in vitro, pH 6.2) [611 multi-frame micrographs composed of 40 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] |
92.7 GB | 2.8 Å | |
2023-03-27 | Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant deltaN6 (in vitro, pH 6.2) [4095 multi-frame micrographs composed of 28 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] |
616.1 GB | 3.0 - 3.4 Å | |
2021-09-01 | Cryo electron microscopy of ex-vivo human SAA amyloid fibrils [6465 multi-frame micrographs composed of 40 frames each in TIFF format] | Schmidt MS [Pubmed: 30846696] [DOI: 10.1038/s41467-019-09033-z] |
1.1 TB | 2.7 Å | |
2021-11-02 | Cryo electron microscopy of ex-vivo murine SAA amyloid fibrils [1429 multi-frame micrographs composed of 40 frames each in TIFF format] | Schmidt MS, Fändrich MF [Pubmed: 30846696] [DOI: 10.1038/s41467-019-09033-z] |
533.9 GB | 3.0 Å | |
2021-11-26 | Cryo electron microscopy of hIAPP fibrils seeded by patient-extracted fibrils [20390 multi-frame micrographs composed of 30 frames each in TIFF format] | Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS [Pubmed: 34518699] [DOI: 10.1038/s41594-021-00646-x] |
9.9 TB | 3.8 - 4.1 Å |