The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2016-06-07 | Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc [multiple data sets in MRC format] | Gao Y [Pubmed: 27281200] [DOI: 10.1038/nature17964] |
93.8 GB | 2.95 Å | |
2016-06-17 | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization [multiple data sets in SPIDER and MRC formats] | Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H [Pubmed: 26449474] [DOI: 10.1126/science.aac5789] |
1.7 TB | 4.7 - 12.5 Å | |
2016-06-20 | Lambda excision HJ intermediate [stack of 66033 particles in MRC format] | Laxmikanthan G, Xu C, Brilot AF, Warren D, Steele L, Seah N, Tong W, Grigorieff N, Landy A, Van Duyne G [Pubmed: 27223329] [DOI: 10.7554/elife.14313] |
4.0 GB | 11.0 Å | |
2016-06-28 | Designer nanoscale DNA assemblies programmed from the top down [50 micrographs in MRC format] | Veneziano R, Ratanalert S, Zhang K, Zhang F, Yan H, Chiu W, Bathe M [Pubmed: 27229143] [DOI: 10.1126/science.aaf4388] |
3.7 GB | 22.0 Å | |
2016-06-28 | Designer nanoscale DNA assemblies programmed from the top down [100 micrographs in MRC format] | Veneziano R, Ratanalert S, Zhang K, Zhang F, Yan H, Chiu W, Bathe M [Pubmed: 27229143] [DOI: 10.1126/science.aaf4388] |
7.3 GB | 25.0 Å | |
2016-06-28 | Designer nanoscale DNA assemblies programmed from the top down [177 micrographs in MRC format] | Veneziano R, Ratanalert S, Zhang K, Zhang F, Yan H, Chiu W, Bathe M [Pubmed: 27229143] [DOI: 10.1126/science.aaf4388] |
13.0 GB | 20.0 Å | |
2016-07-06 | Unsupervised single-particle deep classification via statistical manifold learning [multiple data sets in MRC format] | Wu J, Ma YB, Congdon C, Brett B, Chen S, Xu Y, Ouyang Q, Mao Y | 28.2 GB | — | |
2016-08-03 | Multiple capsid-stabilizing protein-RNA and protein-protein interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis [multiple data sets in MRC and RAW FEI formats] | Shakeel S, Westerhuis BM, Domanska A, Koning RI, Matadeen R, Koster AJ, Bakker AQ, Beaumont T, Wolthers KC, Butcher SJ [Pubmed: 27435188] [DOI: 10.1038/NCOMMS11387] |
3.3 TB | 4.3 Å | |
2016-08-15 | VPP subtomogram averaging [11 class averages in MRC format] | Khoshouei M, Pfeffer S, Baumeister W, Foerster F, Danev R [Pubmed: 27235783] [DOI: 10.1016/j.jsb.2016.05.009] |
33.9 GB | 9.6 Å | |
2016-08-18 | Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin [304 multi-frame micrographs composed of 23 frames each in MRC format] | Vemu A, Atherton J, Spector JO, Szyk A, Moores CA, Roll-Mecak A [Pubmed: 27129203] [DOI: 10.1074/jbc.C116.731133] |
487.7 GB | 4.0 Å | |
2016-09-21 | Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ [751 micrographs in MRC format] | Koning RI, Gomez-Blanco J, Akopjana I, Vargas J, Kazaks A, Tars K, Carazo JM, Koster AJ [Pubmed: 27561669] [DOI: 10.1038/ncomms12524] |
46.9 GB | 5.0 - 10.5 Å | |
2016-09-22 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom (particle images) [stack of 473827 particles in MRC format] | Nguyen TH, Galej WP, Bai XC, Oubridge C, Newman AJ, Scheres SH, Nagai K [Pubmed: 26829225] [DOI: 10.1038/nature16940] |
75.2 GB | 3.7 Å | |
2016-11-10 | Structural basis for dynamic regulation of the human 26S proteasome [multiple data sets in SPIDER and MRC formats] | Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley D, Kirschner MW, Mao Y [Pubmed: 27791164] [DOI: 10.1073/pnas.1614614113] |
2.0 TB | 3.8 - 8.0 Å | |
2016-11-10 | Volta phase plate with defocus cryo-EM dataset of Thermoplasma acidophilum 20S proteasome [427 multi-frame micrographs composed of 24 frames each in TIFF format] | Danev R, Tegunov D, Baumeister W [Pubmed: 28109158] [DOI: 10.1101/085530] |
92.5 GB | 2.2 - 2.4 Å | |
2016-11-11 | Electron cryotomography of cryosectioned budding yeast cells [29 class averages in MRC format] | Chen C, Lim HH, Shi J, Tamura S, Maeshima M, Surana U, Gan L [Pubmed: 27605704] [DOI: 10.1091/mbc.E16-07-0506] |
125.3 GB | — | |
2016-11-18 | Focused Ion Beam-Scanning Electron Microscopy of mitochondrial reticulum in murine skeletal muscle [291 reconstructed volumes in MRC format] | Glancy B, Hartnell LM, Malide D, Yu ZX, Combs CA, Connelly PS, Subramaniam S, Balaban RS [Pubmed: 26223627] [DOI: 10.1038/nature14614] |
1.5 GB | — | |
2016-11-24 | The pathway to GTPase activation of elongation factor SelB on the ribosome [multiple data sets in MRC format] | Fischer N, Neumann P, Bock LV, Maracci C, Wang Z, Paleskava A, Konevega AL, Schroeder GF, Grubmueller H, Rodnina MV, Stark H [Pubmed: 27842381] [DOI: 10.1038/nature20560] |
1.0 TB | 3.4 - 5.3 Å | |
2016-12-02 | CryoEM Dataset of L17-Depleted 50S Ribosomal Intermediates [stack of 131899 particles in MRC format] | Davis JH, Tan YZ, Carragher B, Potter CS, Lyumkis D, Williamson JR [Pubmed: 27912064] [DOI: 10.1016/j.cell.2016.11.020] |
50.3 GB | 3.7 - 7.9 Å | |
2017-02-09 | Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel [multiple data sets in MRC format] | Lee CH, MacKinnon R [Pubmed: 28086084] [DOI: 10.1016/j.cell.2016.12.023] |
66.5 GB | 3.5 Å | |
2017-02-20 | Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate [2261 multi-frame micrographs composed of 40 frames each in TIFF format] | Khoshouei M, Radjainia M, Baumeister W, Danev R [Pubmed: 28665412] [DOI: 10.1038/ncomms16099] |
237.1 GB | 3.2 Å | |
2017-03-13 | Bacteriophage P22 mature virion capsid protein [stack of 45150 particles in IMAGIC format] | Hryc CF, Chen D-H, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W [Pubmed: 28270620] [DOI: 10.1073/pnas.1621152114] |
159.4 GB | 3.3 Å | |
2017-03-15 | Soft X-ray tomography of Plasmodium falciparum infected human erythrocytes stalled in egress by the inhibitors Compound 2 and E64 [1 Soft X-ray tomograms in MRC format] | Hale VL, Saibil HR, Duke E, Fleck RA, Blackman MJ [Pubmed: 28292906] [DOI: 10.1073/pnas.1619441114] |
280.6 MB | — | |
2017-05-15 | Untilted Single-Particle CryoEM of Highly Preferred Orientated Influenza Hemagglutinin Trimer [multiple data sets in MRC format] | Tan YZ, Lyumkis D [Pubmed: 28671674] [DOI: 10.1038/nmeth.4347] |
1.2 TB | 4.2 Å | |
2017-05-24 | Single Particle cryoEM Dataset of TcdA1 in prepore state (SPHIRE tutorial) [97 multi-frame micrographs composed of 24 frames each in MRCS format] | Gatsogiannis C, Roderer D, Raunser S [Pubmed: 28570515] [DOI: 10.3791/55448] |
72.8 GB | 3.5 Å | |
2017-06-01 | The Structure of the Yeast Mitochondrial Ribosome [stack of 2524 particles in MRCS format] | Desai N, Brown A, Amunts A, Ramakrishnan V [Pubmed: 28154081] [DOI: 10.1126/science.aal2415] |
138.6 GB | 3.2 - 4.97 Å |