Electron Microscopy Public Image Archive
Electron Microscopy Public Image Archive
The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
| Release date | Imageset | Title | Authors and references | Size | Resolution |
|---|---|---|---|---|---|
| 2021-12-23 |  |
cryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14 [9765 multi-frame micrographs composed of 60 frames each in TIFF format] | Cao C, Fay J, Roth B [Pubmed: 34789874] [DOI: 10.1038/s41586-021-04126-6] EMD-24897,7s8m |
2.8 TB | 2.54 Å |
| 2022-07-08 |  |
Cryo-EM structure of human KCC1 bound with inhibitor VU0463271 [5833 multi-frame micrographs composed of 40 frames each in TIFF format] | Cao E [Pubmed: 35759661] [DOI: 10.1073/pnas.2109083119] EMD-26116,7tti |
3.9 TB | 3.5 Å |
| 2021-11-26 |  |
Cryo electron microscopy of hIAPP fibrils seeded by patient-extracted fibrils [20390 multi-frame micrographs composed of 30 frames each in TIFF format] | Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS [Pubmed: 34518699] [DOI: 10.1038/s41594-021-00646-x] EMD-23686,EMD-23687,EMD-23688,EMD-23689,7m61,7m62,7m64,7m65 |
9.9 TB | 3.8 - 4.1 Å |
| 2020-08-28 |  |
Cryo-EM structures of four polymorphic TDP-43 amyloid cores [multiple data sets in MRC format] | Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS [Pubmed: 31235914] [DOI: 10.1038/s41594-019-0248-4] EMD-0334,EMD-9339,EMD-9350,EMD-9349,6n3c,6n37,6n3b,6n3a |
4.5 TB | 3.3 - 3.8 Å |
| 2021-11-29 |  |
Cryo electron microscopy of recombinant, un-seeded hIAPP fibrils [6089 multi-frame micrographs composed of 30 frames each in MRC format] | Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS [Pubmed: 32541896] [DOI: 10.1038/s41594-020-0435-3] EMD-21410,6vw2 |
1.9 TB | 3.4 Å |
| 2020-09-28 |  |
Cryo electron microscopy of SARS-CoV-2 stabilized spike in prefusion state [3511 multi-frame micrographs composed of 40 frames each in TIFF format] | Carazo JM [Pubmed: 33063791] [DOI: 10.1107/S2052252520012725] EMD-11341 |
865.0 GB | 2.9 Å |
| 2020-10-12 |  |
Cryo electron microscopy of SARS-CoV-2 spike in prefusion state [3207 multi-frame micrographs composed of 30 frames each in MRC format] | Carazo JM [Pubmed: 33063791] [DOI: 10.1107/S2052252520012725] EMD-11328,EMD-11336,EMD-11337,6zow,6zp5,6zp7 |
2.1 TB | 3.0 - 3.3 Å |
| 2019-10-14 |  |
PolyA polymerase module of the cleavage and polyadenylation factor (CPF) from Saccharomyces cerevisiae [multiple data sets in MRCS format] | Casanal A, Kumar A, Hill CH, Emsley P, Passmore LA [Pubmed: 29074584] [DOI: 10.1126/science.aao6535] EMD-3908,6eoj |
15.4 TB | 3.55 Å |
| 2019-11-19 |  |
Cryo-electron microscopy structure of the P-Rex1–G-beta-gamma signaling scaffold [multiple data sets in TIFF, MRC and MRCS formats] | Cash JN, Urata S, Li S, Ravala SK, Avramova LV, Shost MD, Gutkind JS, Tesmer JJG, Cianfrocco MA [Pubmed: 31663027] [DOI: 10.1126/sciadv.aax8855] EMD-20308,6pcv |
3.0 TB | 3.2 Å |
| 2022-02-01 |  |
Nudaurelia capensis omega virus procapsid: virus-like particles expressed in Nicotiana benthamiana [multiple data sets in MRC format] | Castells-Graells R, Ribeiro JRS, Domitrovic T, Hesketh EL, Scarff CA, Johnson JE, Ranson NA, Lawson DM, Lomonossoff GP [Pubmed: 34031522] [DOI: 10.1038/s42003-021-02134-w] EMD-11911,7ata |
1.0 TB | 6.63 Å |
| 2022-02-04 |  |
Nudaurelia capensis omega virus capsid: virus-like particles expressed in Nicotiana benthamiana [multiple data sets in MRC format] | Castells-Graells R, Ribeiro JRS, Domitrovic T, Hesketh EL, Scarff CA, Johnson JE, Ranson NA, Lawson DM, Lomonossoff GP [Pubmed: 34031522] [DOI: 10.1038/s42003-021-02134-w] EMD-11830,7anm |
5.3 TB | 2.72 Å |
| 2021-05-25 |  |
Structural basis of ω-3 fatty acid transport across the blood-brain barrier [15516 multi-frame micrographs composed of 50 frames each in TIFF format] | Cater RJ, Chua GL, Erramilli SK, Keener JE, Choy BC, Tokarz P, Chin CF, Quek DQY, Kloss B, Pepe JG, Parisi G, Wong BH, Clarke OB, Marty MT, Kossiakoff AA, Khelashvilli G, Silver DL, Mancia F [Pubmed: 34135507] [DOI: 10.1038/s41586-021-03650-9] EMD-23883,7mjs |
3.9 TB | 3.03 Å |
| 2023-01-18 |  |
Organizing Structural Principles of the Interleukin-17 Ligand-Receptor Axis [multiple data sets in TIFF format] | Caveney NA, Wilson SC, Garcia KC [Pubmed: 35863378] [DOI: 10.1038/s41586-022-05116-y] EMD-26833,EMD-26834,EMD-26835,EMD-26836,EMD-26837,7uwj,7uwk,7uwl,7uwm,7uwn |
17.7 TB | 2.5 - 4.4 Å |
| 2020-08-18 |  |
Mechanism of Ribosome Rescue by Alternative Release Factor B [multiple data sets in MRC format] | Chan K-H, Petrychenko V, Mueller C, Maracci C, Holtkamp W, Wilson DN, Fischer N, Rodnina MV [Pubmed: 32796827] [DOI: 10.1038/s41467-020-17853-7] EMD-10905,EMD-10906,EMD-10907,EMD-10908,6ysr,6yss,6yst,6ysu |
788.2 GB | 2.6 - 3.7 Å |
| 2021-03-29 |  |
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E [multiple data sets in MRC and MRCS formats] | Chandler-Bostock R, Mata CP, Bingham RJ, Dykeman EC, Meng B, Tuthill TJ, Rowlands DJ, Ranson NA, Twarock R, Stockley PG [Pubmed: 33370422] [DOI: 10.1371/journal.ppat.1009146] EMD-10504,6thd |
635.4 GB | 2.23 Å |
| 2017-07-14 |  |
Tilt-series for the electron cryotomogram of Vibrio cholerae O395 N1 [16 tilt series in MRC format] | Chang YW, Kjaer A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ [Pubmed: 28165453] [DOI: 10.1038/nmicrobiol.2016.269] EMD-8492,EMD-8493,EMD-8494,EMD-8495,EMD-3792 |
51.3 GB | 50.0 Å |
| 2019-09-30 |  |
Human pre-B spliceosome and U4/U6.U5 tri-snRNP [multiple data sets in MRC and MRCS formats] | Charenton C, Wilkinson ME, Nagai K [Pubmed: 30975767] [DOI: 10.1126/science.aax3289] EMD-4658,EMD-4673,EMD-4672,EMD-4674,EMD-4675,EMD-4676,EMD-4686,EMD-4665,EMD-4687,EMD-4688,EMD-4689,EMD-4690,6qw6,6qx9 |
2.3 TB | 2.9 - 28.0 Å |
| 2022-11-11 |  |
Single particle cryo-EM of SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76 [4197 multi-frame micrographs composed of 40 frames each in TIFF format] | Chaves-Sanjuan A, Bolognesi M [Pubmed: 36114671] [DOI: 10.1016/j.ymthe.2022.09.010] EMD-14628,7zce |
3.0 TB | 3.5 Å |
| 2023-01-03 |  |
Cryo-EM structure of hnRNPDL amyloid fibrils [multiple data sets in TIFF format] | Chaves-Sanjuan A, Garcia-Pardo J, Bartolome-Nafria A, Gil-Garcia M, Visentin C, Bolognesi M, Ricagno S, Ventura S EMD-14738,7zir |
880.1 GB | 2.5 Å |
| 2016-11-11 |  |
Electron cryotomography of cryosectioned budding yeast cells [29 class averages in MRC format] | Chen C, Lim HH, Shi J, Tamura S, Maeshima M, Surana U, Gan L [Pubmed: 27605704] [DOI: 10.1091/mbc.E16-07-0506] EMD-8157 |
125.3 GB | — |
| 2018-10-25 |  |
CryoET of bacterial RNA polymerase with several detergents [multiple data sets in MRC and RAW TEXT formats] | Chen J, Noble AJ, Kang JY, Darst SA | 207.5 GB | — |
| 2022-11-11 |  |
Cryo-EM structure of full-length human immunoglobulin M [43331 micrographs in MRC format] | Chen Q, Rosenthal PB, Tolar P [Pubmed: 36274064] [DOI: 10.1038/s41467-022-34090-2] EMD-13921 |
2.6 TB | 4.4 Å |
| 2016-11-10 |  |
Structural basis for dynamic regulation of the human 26S proteasome [multiple data sets in SPIDER and MRC formats] | Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley D, Kirschner MW, Mao Y [Pubmed: 27791164] [DOI: 10.1073/pnas.1614614113] EMD-8332,EMD-8333,EMD-8334,EMD-8335,EMD-8336,EMD-8337,5t0c,5t0g,5t0h,5t0i,5t0j |
2.0 TB | 3.8 - 8.0 Å |
| 2020-03-20 |  |
Cryo Electron Tomograms of Membrane Fractions of Rabbit Skeletal Muscle for Structural Determination of RyR1 in SR Vesicles [82 tilt series in MRC format] | Chen W, Kudryashev M [Pubmed: 32147968] [DOI: 10.15252/embr.201949891] EMD-10637,EMD-10638,EMD-10639,EMD-10640,EMD-10641,EMD-10642,EMD-10643,EMD-10644,EMD-10645,EMD-10646 |
254.2 GB | 12.6 - 38.0 Å |
| 2020-12-09 |  |
SA-like and SD-like states of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A [6216 micrographs in MRC format] | Chen X, Walters KJ [Pubmed: 32783951] [DOI: 10.1016/j.str.2020.07.011] EMD-21691,EMD-21696,EMD-21704,6wjd,6wjn |
330.3 GB | 4.1 - 5.7 Å |
