The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2020-04-09 | Cryo-EM structure of Lumazine Synthase [1198 multi-frame micrographs composed of 41 frames each in MRC format] | Bhella D, Streetley J, Clarke M, Cowton V, Patel A [Pubmed: 31359340] [DOI: 10.1007/s12551-019-00571-w] EMD-10736 |
3.0 TB | 2.0 Å | |
2020-04-09 | Cryo-EM structure of Lumazine Synthase [2874 multi-frame micrographs composed of 39 frames each in MRC format] | Bhella D, Streetley J, Clarke M, Cowton V, Patel A [Pubmed: 31359340] [DOI: 10.1007/s12551-019-00571-w] EMD-10736 |
6.8 TB | 2.0 Å | |
2022-09-26 | In situ cryo-electron tomography of autophagic structures in S. cerevisiae [84 tilt series in MRC format] | Bieber A, Capitanio C, Erdmann PS, Schulman BA, Baumeister W, Wilfling F [Pubmed: 36122245] [DOI: 10.1073/pnas.2209823119] EMD-15526,EMD-15545,EMD-15546,EMD-15547,EMD-15548,EMD-15549 |
249.0 GB | — | |
2020-07-14 | 3 Å resolution single particle reconstruction of glucosyltransferase ALG6 in nanodisc [multiple data sets in MRC and TIFF formats] | Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP [Pubmed: 32103179] [DOI: 10.1038/s41586-020-2044-z] EMD-10258,6sni |
2.8 TB | 3.0 Å | |
2018-08-09 | Three-dimensional nanostructure of an intact microglia cell [multiple data sets in TIFF and IMOD formats] | Bolasco G, Weinhard L, Boissonnet T, Neujahr R, Gross CT | 7.4 GB | — | |
2022-04-19 | Cryo-EM micrographs of BMV TLS RNA [multiple data sets in MRC format] | Bonilla SL, Sherlock ME, MacFadden A, Kieft JS [Pubmed: 34793227] [DOI: 10.1126/science.abe8526] EMD-24952,7sam |
6.7 TB | 4.3 Å | |
2015-08-28 | Cryo electron microscopy of YnaI [multiple data sets in MRC format] | Bottcher B, Prazak V, Rasmussen A, Black SS, Rasmussen T [Pubmed: 26256535] [DOI: 10.1016/j.str.2015.06.023] EMD-3035 |
107.6 GB | 12.6 Å | |
2022-09-23 | Single particle reconstruction of the MAPK p38alpha in complex with its activating MAP2K MKK6 [multiple data sets in TIFF format] | Bowler MW, Juyoux P, Pellegrini E EMD-15233,8a8m |
4.0 TB | 4.0 Å | |
2022-01-12 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA/Fdx [401 multi-frame micrographs composed of 50 frames each in TIFF format] | Boyaci H, Chen J, Darst SA, Campbell EA [Pubmed: 29480804] [DOI: 10.7554/eLife.34823] EMD-7319,6bzo |
220.5 GB | 3.38 Å | |
2022-01-12 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA [1381 multi-frame micrographs composed of 50 frames each in TIFF format] | Boyaci H, Chen J, Darst SA, Campbell EA [Pubmed: 29480804] [DOI: 10.7554/elife.34823] |
838.9 GB | — | |
2022-01-17 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA bound to an inhibitor corallopyronin and us-fork DNA [multiple data sets in TIFF format] | Boyaci H, Chen J, Darst SA, Campbell EA [Pubmed: 30626968] [DOI: 10.1038/s41586-018-0840-5] EMD-9041,6eec |
2.3 TB | 3.55 Å | |
2022-01-28 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA bound to an inhibitor corallopyronin and de novo melted AP3 promoter DNA [multiple data sets in TIFF format] | Boyaci H, Chen J, Jansen R, Darst SA, Campbell EA [Pubmed: 30626968] [DOI: 10.1038/s41586-018-0840-5] EMD-9041,6eec |
1.8 TB | 3.55 Å | |
2022-01-28 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA bound to the de novo melted AP3 promoter DNA [8579 multi-frame micrographs composed of 50 frames each in MRC format] | Boyaci H, Chen J, Jansen R, Darst SA, Campbell EA [Pubmed: 30626968] [DOI: 10.1038/s41586-018-0840-5] EMD-9037,6edt |
1.8 TB | — | |
2022-01-28 | CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA bound to the Fdx and upstream fork DNA [multiple data sets in MRC format] | Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA [Pubmed: 29480804] [DOI: 10.7554/elife.34823] |
2.0 TB | — | |
2022-05-26 | Cryo TEM single particle dataset of purified ChAdOx1/ADZ-1222 [2875 multi-frame micrographs composed of 40 frames each in TIFF format] | Boyd RJ, Baker AB [Pubmed: 34851659] [DOI: 10.1126/sciadv.abl8213] EMD-24408,7rd1 |
1.0 TB | 3.07 Å | |
2021-03-03 | Cryo electron microscopy of alpha-synuclein H50Q fibrils [3577 multi-frame micrographs composed of 30 frames each in MRC format] | Boyer DR, Li B, Sun C, Fan W, Sawaya MR, Jiang L, Eisenberg DS [Pubmed: 31695184] [DOI: 10.1038/s41594-019-0322-y] EMD-20328,6peo |
595.3 GB | 3.3 Å | |
2020-10-28 | The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure [4919 multi-frame micrographs composed of 30 frames each in TIFF format] | Boyer DR, Li B, Sun C, Fan W, Zhou K, Hughes MP, Sawaya MR, Jiang L, Eisenberg DS [Pubmed: 32015135] [DOI: 10.1073/pnas.1917914117] EMD-20759,6ufr |
897.9 GB | 2.5 Å | |
2019-04-18 | CryoET of cis-mutated mouse protocadherin gamma B6 on membranes [multiple data sets in MRC format] | Brasch J, Bepler T, Berger B, Maniatis T, Potter CS, Carragher B, Honig B, Shapiro L [Pubmed: 30971825] [DOI: 10.1038/s41586-019-1089-3] EMD-9200 |
379.7 GB | — | |
2019-04-18 | CryoET of mouse protocadherin gamma B6 on membranes (with energy filter) [multiple data sets in MRC format] | Brasch J, Goodman KM, Noble AJ, Mannepalli S, Bahna F, Rapp M, Dandey VP, Bepler T, Berger B, Maniatis T, Carragher B [Pubmed: 30971825] [DOI: 10.1038/s41586-019-1089-3] EMD-9199 |
411.3 GB | — | |
2019-04-18 | Single particle cryo electron tomography of mouse protocadherin gamma B6 [multiple data sets in MRC format] | Brasch J, Goodman KM, Noble AJ, Mannepalli S, Bahna F, Rapp M, Dandey VP, Bepler T, Berger B, Maniatis T, Potter CS, Carragher B, Honig B, Shapiro L [Pubmed: 30971825] [DOI: 10.1038/s41586-019-1089-3] EMD-9197 |
384.1 GB | 35.0 Å | |
2019-04-18 | CryoET of mouse protocadherin gamma B6 on membranes (without energy filter) [multiple data sets in MRC format] | Brasch J, Goodman KM, Noble AJ, Mannepalli S, Bahna F, Rapp M, Dandey VP, Bepler T, Berger B, Maniatis T, Potter CS, Carragher B, Honig B, Shapiro L [Pubmed: 30971825] [DOI: 10.1038/s41586-019-1089-3] EMD-9198 |
363.4 GB | — | |
2019-04-18 | Single particle cryoEM of mouse protocadherin gamma B6 [multiple data sets in MRC format] | Brasch J, Goodman KM, Potter CS, Carragher B, Honig B, Shapiro L, Noble AJ, Mannepalli S, Bahna F, Rapp M, Dandey VP, Bepler T, Berger B, Maniatis T [Pubmed: 30971825] [DOI: 10.1038/s41586-019-1089-3] EMD-9197,EMD-9200,EMD-9199,EMD-9198 |
438.8 GB | 35.0 Å | |
2020-05-27 | 2.7 Angstrom cryo-EM reconstructions of glucose isomerase in the presence of substantial aberrations [202 multi-frame micrographs composed of 200 frames each in MRCS format] | Bromberg R, Guo Y, Borek D, Otwinowski Z EMD-21371,6vrs |
1.0 TB | 2.7 Å | |
2020-05-27 | 2.6 Angstrom cryo-EM reconstructions of HemQ from Geobacillus in the presence of substantial aberrations [257 multi-frame micrographs composed of 100 frames each in MRCS format] | Bromberg R, Guo Y, Borek D, Otwinowski Z EMD-21376,6vsc |
1.3 TB | 2.6 Å | |
2020-05-26 | 2.3 Angstrom cryo-EM reconstructions of HemQ from Geobacillus [258 multi-frame micrographs composed of 100 frames each in MRCS format] | Bromberg R, Guo Y, Borek D, Otwinowski Z EMD-21373,6vsa |
1.4 TB | 2.32 Å |