The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2022-11-14 | Cryo-EM structure of streptavidin on ultraflat graphene film [2371 multi-frame micrographs composed of 32 frames each in MRCS format] | Zheng LM, Liu N, Wang HW, Peng HL | 685.7 GB | 2.2 Å | |
2022-05-31 | Cryo-EM structure of human NKCC1 K289NA492E bound with bumetanide [4273 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao YZ [Pubmed: 35585053] [DOI: 10.1038/s41467-022-30407-3] |
2.1 TB | 3.6 Å | |
2022-05-27 | Cryo-EM structure of human NKCC1 K289NA492EL671C bound with bumetanide [3891 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao YZ [Pubmed: 35585053] [DOI: 10.1038/s41467-022-30407-3] |
1.8 TB | 2.9 Å | |
2022-01-21 | Cryo-EM reveals the stochastic nature of individual ATP binding events in a group II chaperonin [stack of 165212 particles in MRCS format] | Zhao Y, Schmid MF, Frydman J, Chiu W [Pubmed: 34362932] [DOI: 10.1038/s41467-021-25099-0] |
48.4 GB | 3.9 - 6.4 Å | |
2022-05-27 | Cryo-EM structure of human NKCC1 K289NA492E bound with Furosemide [3405 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao Y [Pubmed: 35585053] [DOI: 10.1038/s41467-022-30407-3] |
1.6 TB | 3.4 Å | |
2020-03-10 | Cryo-EM of GLP-1 receptor bound to TT-OAD2 non-peptidic agonist [multiple data sets in TIFF format] | Zhao P, Liang YL, Belousoff MJ, Deganutti G, Fletcher MM, Willard FS, Bell MG, Christe ME, Sloop KW, Inoue A, Truong TT, Clydesdale L, Furness SGB, Christopoulos A, Wang MW, Miller LJ, Reynolds CA, Danev R, Sexton PM, Wootten D [Pubmed: 31915381] [DOI: 10.1038/s41586-019-1902-z] |
6.2 TB | 3.0 Å | |
2022-10-14 | The structure of hemolysin A secretion system, wild-type HlyB/D complex without nucleotide. [multiple data sets in TIFF and MRC formats] | Zhao H, Chen J [Pubmed: 36055198] [DOI: 10.1016/j.cell.2022.07.017] |
3.5 TB | 2.9 Å | |
2022-10-14 | The structure of hemolysin A secretion system, HlyB(E631Q)/D complex with ATPMg. [12543 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao H, Chen J [Pubmed: 36055198] [DOI: 10.1016/j.cell.2022.07.017] |
5.4 TB | 3.4 Å | |
2024-01-15 | Structure of Bre1-nucleosome complex [4561 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao F, Hicks CW, Wolberger C [Pubmed: 37872231] [DOI: 10.1038/s41594-023-01137-x] |
972.6 GB | 3.47 Å | |
2020-10-09 | mouse cGAS with nucleosomes from 293T [2979 multi-frame micrographs composed of 40 frames each in MRC format] | Zhao B, Xu P, Rowlett CM, Jing T, Shinde O, Lei Y, West AP, Liu WR, Li P [Pubmed: 32911481] [DOI: 10.1038/s41586-020-2749-z] |
1.5 TB | 4.36 Å | |
2020-10-09 | mouse cGAS with reconstituted nucleosome [5353 multi-frame micrographs composed of 40 frames each in MRC format] | Zhao B, Xu P [Pubmed: 32911481] [DOI: 10.1038/s41586-020-2749-z] |
767.6 GB | 2.98 Å | |
2019-06-21 | Cryo electron micrographs of human cystic fibrosis transmembrane conductance regulator (CFTR) in complex with GLPG [3335 multi-frame micrographs composed of 50 frames each in TIFF format] | Zhang ZZ, Liu FL, Chen JC [Pubmed: 31221859] [DOI: 10.1126/science.aaw7611] |
1.4 TB | 3.2 Å | |
2023-01-10 | Cryo-EM raw image of Bovine retinal pigmented epithelium lysate [multiple data sets in TIFF format] | Zhang Z., Morgan C.E. [Pubmed: 36577381] [DOI: 10.1016/j.celrep.2022.111876] |
1.8 TB | 2.28 - 3.32 Å | |
2022-09-09 | Structure of SARS-CoV-2 membrane protein [multiple data sets in TIFF format] | Zhang Z, Ohto U, Shimizu T [Pubmed: 35931673] [DOI: 10.1038/s41467-022-32019-3] |
4.4 TB | 2.7 - 6.2 Å | |
2021-11-08 | Hedgehog receptor Patched (PTCH1) in complex with a conformation selective nanobody TI23 [stack of 307652 particles in MRCS format] | Zhang Y, Lu WJ, Bulkley DP, Liang J, Ralko A, Han S, Roberts KJ, Li A, Cho W, Cheng Y, Manglik A, Beachy PA [Pubmed: 33139559] [DOI: 10.1073/pnas.2011560117] |
75.2 GB | 3.4 Å | |
2021-01-22 | Lipid-stabilised asymmetric open state of the 5-HT3A serotonin receptor [multiple data sets in MRC format] | Zhang Y, Dijkman PM, Zou R, Zandl-Lang M, Sanchez RM, Eckhardt-Strelau L, Köfeler H, Vogel H, Yuan S, Kudryashev M [Pubmed: 33594077] [DOI: 10.1038/s41467-021-21016-7] |
6.4 TB | 2.8 - 3.2 Å | |
2023-03-13 | Tilt series of authentic mumps virus nucleocapsid isolated from lysate of chronically infected HeLa cells under arsenite stress [840 tilt series in TIFF format] | Zhang X, Mahamid J | 27.9 GB | 4.5 - 6.3 Å | |
2021-06-04 | Cryo-EM of GLP-1 receptor bound to GLP-1 and Gs protein [5739 multi-frame micrographs composed of 75 frames each in TIFF format] | Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D [Pubmed: 33027691] [DOI: 10.1016/j.molcel.2020.09.020] |
1.9 TB | 2.1 Å | |
2019-04-12 | Cryo-EM reconstruction of heparin-induced 2N3R tau filaments [multiple data sets in MRC and MRCS formats] | Zhang W., Falcon B., Murzin A.G., Fan J, Crowther R.A., Goedert M., Scheres S.H.W. [Pubmed: 30720432] [DOI: 10.7554/eLife.43584] |
4.8 TB | 3.7 Å | |
2019-03-22 | Cryo-EM reconstruction of heparin-induced 2N4R tau filaments [multiple data sets in MRC and TIFF formats] | Zhang W., Falcon B., Murzin A.G., Fan J, Crowther R.A., Goedert M., Scheres S.H.W. [Pubmed: 30720432] [DOI: 10.7554/eLife.43584] |
446.3 GB | 3.3 - 3.5 Å | |
2020-03-02 | Cryo-EM reconstruction of tau filaments extracted from the brains of three individuals with Corticobasal degeneration [multiple data sets in TIFF format] | Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW [Pubmed: 32050258] [DOI: 10.1038/s41586-020-2043-0] |
2.8 TB | 3.0 - 3.2 Å | |
2022-01-31 | Asymmetric structures of the uncleaved full-length HIV-1 envelope glycoprotein trimer [multiple data sets in MRC and BIG DATA VIEWER HDF5 formats] | Zhang S, Wang KY, Wang WL, Chen S, Sodroski JG, Mao Y [Pubmed: 34549974] [DOI: 10.1128/JVI.00529-21] |
4.0 TB | 4.1 - 4.7 Å | |
2015-08-12 | Cryo-EM micrographs of microtubules in GDP-state obtained by copolymerization with EB3 [multiple data sets in MRC format] | Zhang R, Alushin GM, Brown A, Nogales E [Pubmed: 26234155] [DOI: 10.1016/j.cell.2015.07.012] |
426.0 GB | 3.4 Å | |
2023-08-25 | MCRV virus [4271 multi-frame micrographs composed of 16 frames each in MRCS format] | Zhang Q, Jiang W [Pubmed: 37083840] [DOI: 10.1371/journal.ppat.1011341] |
4.2 TB | 3.1 - 3.7 Å | |
2016-06-17 | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization [multiple data sets in SPIDER and MRC formats] | Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H [Pubmed: 26449474] [DOI: 10.1126/science.aac5789] |
1.7 TB | 4.7 - 12.5 Å |