The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2018-10-23 | Cryo-electron microscopy data of thermostabilized avian CFTR [stack of 2 particles in MRCS format] | Fay JF [Pubmed: 30281975] [DOI: 10.1021/acs.biochem.8b00763] |
19.3 GB | 4.3 - 6.6 Å | |
2018-10-25 | Structure of the Macrobrachium rosenbergii Nodavirus: A new genus within the Nodaviridae? [2459 micrographs in MRC format] | Ho KL, Gabrielsen M, Beh PL, Kueh CL, Thong QX, Streetley J, Tan WS, Bhella D [Pubmed: 30346944] [DOI: 10.1371/journal.pbio.3000038] |
130.4 GB | 3.28 Å | |
2018-10-25 | CryoET of bacterial RNA polymerase with several detergents [multiple data sets in MRC and RAW TEXT formats] | Chen J, Noble AJ, Kang JY, Darst SA [DOI: 10.1016/j.yjsbx.2019.100005] |
207.5 GB | — | |
2018-10-25 | Cryo-EM structure of mouse heavy-chain apoferritin at 1.62 A [1647 multi-frame micrographs composed of 59 frames each in MRC format] | Danev R, Yanagisawa H, Kikkawa M [Pubmed: 31078399] [DOI: 10.1016/j.tibs.2019.04.008] |
1.2 TB | 1.62 Å | |
2018-10-25 | Thermoplasma acidophilum 20S [1175 multi-frame micrographs composed of 50 frames each in MRC format] | Eng ET, Kopylov M, Negro CJ, Dallaykan S, Rice WJ, Jordan KJ, Kelley K, Carragher BO, Potter CS | 1.5 TB | 2.1 Å | |
2018-11-23 | Cryo-EM Reconstruction of apo EsCas13d [multiple data sets in MRCS format] | Zhang C, Lyumkis D [Pubmed: 30241607] [DOI: 10.1016/j.cell.2018.09.001] |
66.9 GB | 6.5 Å | |
2018-12-13 | Beta-2-microglobulin fibrils with multiple polymorphs formed at pH 2 [5549 micrographs in MRC format] | Iadanza MG [Pubmed: 30375379] [DOI: 10.1038/s41467-018-06761-6] |
294.3 GB | 3.975 Å | |
2019-01-17 | CryoEM reconstruction of native lens connexin-46/50 at 3.4 angstrom resolution [multiple data sets in MRC format] | Myers JB, Reichow SL [Pubmed: 30542154] [DOI: 10.1038/s41586-018-0786-7] |
774.5 GB | 3.4 Å | |
2019-01-18 | Calicivirus VP2 forms a portal to mediate endosome escape [5198 micrographs in MRC format] | Conley MJ, McElwee M, Azmi LB, Gabrielsen M, Byron O, Goodfellow IG, Bhella D [Pubmed: 30626974] [DOI: 10.1038/s41586-018-0852-1] |
324.9 GB | 3.0 Å | |
2019-01-18 | Calicivirus VP2 forms a portal to mediate endosome escape [13872 micrographs in MRC format] | Conley MJ, McElwee M, Azmi LB, Gabrielsen M, Byron O, Goodfellow IG, Bhella D [Pubmed: 30626974] [DOI: 10.1038/s41586-018-0852-1] |
867.0 GB | 3.75 Å | |
2019-01-29 | afTMEM16/nanodisc complex in the presence of Ca2+ and 5mol% Ceramide 24:0 [2145 micrographs in MRC format] | Falzone M. E., Accardi A [Pubmed: 30648972] [DOI: 10.7554/eLife.43229] |
113.8 GB | 3.59 Å | |
2019-01-29 | afTMEM16/nanodisc complex in the presence of Ca2+ [2838 micrographs in MRC format] | Falzone M. E., Accardi A [Pubmed: 30648972] [DOI: 10.7554/eLife.43229] |
150.5 GB | 4.05 Å | |
2019-01-30 | afTMEM16/nanodisc complex in the absence of Ca2+ [3054 micrographs in MRC format] | Falzone ME, Rheinberger J, Di Lorenzo A, Accardi A [Pubmed: 31278385] [DOI: 10.1038/s41586-019-1377-y] |
162.0 GB | 4.2 Å | |
2019-02-01 | Cryo electron micrographs of RNA polymerase II transcribing a nucleosome [2719 multi-frame micrographs composed of 40 frames each in TIFF format] | Kujirai T, Ehara H, Fujino Y, Shirouzu M, Sekine S, Kurumizaka H [Pubmed: 30287617] [DOI: 10.1126/science.aau9904] |
1.4 TB | 7.0 Å | |
2019-02-01 | Bdellovibrio electron cryotomography tilt-series acquired by continuous tilting [1 tilt series in MRC format] | Chreifi G, Chen S, Metskas LA, Kaplan M, Jensen GJ [Pubmed: 30639925] [DOI: 10.1016/j.jsb.2018.12.008] |
2.1 GB | — | |
2019-02-01 | Bdellovibrio bacteriovorus electron cryotomography tilt-series acquired by fast-incremental method [1 tilt series in MRC format] | Chreifi G, Chen S, Metskas LA, Kaplan M, Jensen GJ [Pubmed: 30639925] [DOI: 10.1016/j.jsb.2018.12.008] |
5.2 GB | — | |
2019-02-19 | The 1.54 Å structure of Apoferritin by CRYOARM300 with cold-FEG [972 multi-frame micrographs composed of 50 frames each in TIFF format] | Kato T, Makino F, Nakane T, Terahara N, Kaneko T, Shimizu Y, Motoki S, Ishikawa I, Yonekura K, Namba K [DOI: 10.1017/S1431927619005725] |
145.9 GB | 1.54 Å | |
2019-02-20 | Cryo electron microscopy of tau filaments from sporadic Alzheimer's disease brain [507 micrographs in MRC format] | Falcon B, Zhang W, Schweighauser M, Murzin AG, Vidal R, Garringer HJ, Ghetti B, Scheres SHW, Goedert M [Pubmed: 30276465] [DOI: 10.1007/s00401-018-1914-z] |
27.0 GB | 3.2 Å | |
2019-03-18 | Horse liver alcohol dehydrogenase movies obtained using Talos Arctica operating at 200 kV equipped with a K2 [1153 multi-frame micrographs composed of 44 frames each in MRC format] | Herzik Jr MA, Wu M, Lander GC [Pubmed: 30833564] [DOI: 10.1038/s41467-019-08991-8] |
146.2 GB | 2.9 Å | |
2019-03-18 | Human methemoglobin movies obtained using Talos Arctica operating at 200 kV equipped with a K2 [1665 multi-frame micrographs composed of 44 frames each in MRC format] | Herzik Jr MA, Wu M, Lander GC [Pubmed: 30833564] [DOI: 10.1038/s41467-019-08991-8] |
1.9 TB | 2.8 - 3.2 Å | |
2019-03-22 | Cryo-EM reconstruction of heparin-induced 2N4R tau filaments [multiple data sets in MRC and TIFF formats] | Zhang W., Falcon B., Murzin A.G., Fan J, Crowther R.A., Goedert M., Scheres S.H.W. [Pubmed: 30720432] [DOI: 10.7554/eLife.43584] |
446.3 GB | 3.3 - 3.5 Å | |
2019-03-25 | Catalytic subunit of protein kinase A bound to ATP, manganese, and IP20 movies obtained using Talos Arctica operating at 200 kV equipped with a K2 [4812 multi-frame micrographs composed of 44 frames each in MRC format] | Herzik Jr MA, Wu M, Lander GC [Pubmed: 30833564] [DOI: 10.1038/s41467-019-08991-8] |
619.6 GB | 6.0 Å | |
2019-04-05 | mouse MDA5-dsRNA 10mM ATP Filamemt [2213 micrographs in MRC format] | Yu Q, Qu K, Modis YE [Pubmed: 30449722] [DOI: 10.1016/j.molcel.2018.10.012] |
138.9 GB | 3.87 Å | |
2019-04-05 | mouse MDA5-dsRNA 2.5-mM AMPPNP Filamemt [471 multi-frame micrographs composed of 75 frames each in MRC format] | Yu Q, Qu K, Modis YE [Pubmed: 30449722] [DOI: 10.1016/j.molcel.2018.10.012] |
1.1 TB | 4.06 Å | |
2019-04-05 | mouse MDA5-dsRNA filaments [592 multi-frame micrographs composed of 27 frames each in MRC format] | Yu Q, Qu K, Modis YE [Pubmed: 30449722] [DOI: 10.1016/j.molcel.2018.10.012] |
499.5 GB | 4.02 - 4.16 Å |