The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2020-12-21 | CEM500K - A large-scale heterogeneous unlabeled cellular electron microscopy image dataset for deep learning. [496544 micrographs in TIFF format] | Conrad RW, Narayan K [DOI: 10.1101/2020.12.11.421792] |
16.6 GB | — | |
2021-05-28 | CLEM/FIB-SEM Imaging of T Cells after the Formation of Signaling Microclusters at the Immunological Synapse [160 micrographs in TIFF format] | Narayan K | 26.6 MB | — | |
2022-12-19 | CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM. [multiple data sets in TIFF format] | Lleti JMSL, Steyer AMS, Schwab YS | 19.7 GB | — | |
2019-01-18 | Calicivirus VP2 forms a portal to mediate endosome escape [13872 micrographs in MRC format] | Conley MJ, McElwee M, Azmi LB, Gabrielsen M, Byron O, Goodfellow IG, Bhella D [Pubmed: 30626974] [DOI: 10.1038/s41586-018-0852-1] |
867.0 GB | 3.75 Å | |
2019-01-18 | Calicivirus VP2 forms a portal to mediate endosome escape [5198 micrographs in MRC format] | Conley MJ, McElwee M, Azmi LB, Gabrielsen M, Byron O, Goodfellow IG, Bhella D [Pubmed: 30626974] [DOI: 10.1038/s41586-018-0852-1] |
324.9 GB | 3.0 Å | |
2023-09-22 | Carboxysome minishell containing CsoS1A4A and CsoS2 [20277 multi-frame micrographs composed of 50 frames each in TIFF format] | Ni T, Jiang Q, Ng PC, Dou H, Liu LN, Zhang P [Pubmed: 37679318] [DOI: 10.1038/s41467-023-41211-y] |
6.9 TB | 1.86 - 2.52 Å | |
2023-09-22 | Carboxysome minishell containing CsoS1A4A and truncated CsoS2 [13151 multi-frame micrographs composed of 40 frames each in TIFF format] | Ni T, Jiang Q, Ng PC, Dou H, Liu LN, Zhang P [Pubmed: 37679318] [DOI: 10.1038/s41467-023-41211-y] |
2.2 TB | 2.02 - 3.29 Å | |
2020-04-21 | Cardiac thin filament in low calcium state [8820 multi-frame micrographs composed of 50 frames each in TIFF format] | Oda T, Yanagisawa HA, Wakabayashi T [Pubmed: 31954841] [DOI: 10.1016/j.jsb.2020.107450] |
2.5 TB | 3.0 - 12.0 Å | |
2021-06-11 | Cas6-reverse transcriptase-Cas1—Cas2 CRISPR integrase complex [3330 multi-frame micrographs composed of 50 frames each in TIFF format] | Hoel CM, Wang JY, Doudna JA, Brohawn SG [Pubmed: 33958590] [DOI: 10.1038/s41467-021-22900-y] |
2.2 TB | 3.4 - 3.9 Å | |
2019-03-25 | Catalytic subunit of protein kinase A bound to ATP, manganese, and IP20 movies obtained using Talos Arctica operating at 200 kV equipped with a K2 [4812 multi-frame micrographs composed of 44 frames each in MRC format] | Herzik Jr MA, Wu M, Lander GC [Pubmed: 30833564] [DOI: 10.1038/s41467-019-08991-8] |
619.6 GB | 6.0 Å | |
2023-01-30 | ChRmine in MSP1E3D1 lipid nanodisc [10903 multi-frame micrographs composed of 50 frames each in TIFF format] | Tucker K, Sridharan S, Adesnik H, Brohawn SG [Pubmed: 35977941] [DOI: 10.1038/s41467-022-32441-7] |
7.0 TB | 2.74 Å | |
2020-06-16 | Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis [multiple data sets in TIFF and MRC formats] | Herrera NG, Morano NC, Celikgil A, Georgiev GI, Malonis R, Lee JH, Tong K, Vergnolle O, Massimi A, Yen LY, Noble AJ, Kopylov M, Bonanno JB, Garrett-Thomson SC, Hayes DB, Bortz R, Wirchnianski A, Florez C, Laudermilch E, Haslwanter D, Fels J, Dieterle M, Jangra R, Barnhill J, Mengotto A, Kimmel D, Daily J, Pirofski L, Chandran K, Brenowitz M, Garforth S, Eng E, Lai JR, Almo SC [Pubmed: 32587972] [DOI: 10.1101/2020.06.14.150607] |
484.3 GB | 3.22 Å | |
2020-08-11 | Chicken CALHM1 - Human CALHM2 chimera [10927 multi-frame micrographs composed of 30 frames each in TIFF format] | Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H [Pubmed: 31988524] [DOI: 10.1038/s41594-019-0369-9] |
1.1 TB | 3.87 Å | |
2020-08-11 | Chicken CALHM1, 1 mM EDTA [10513 multi-frame micrographs composed of 50 frames each in TIFF format] | Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H [Pubmed: 31988524] [DOI: 10.1038/s41594-019-0369-9] |
2.4 TB | 3.63 Å | |
2022-10-28 | Chlamydomonas Cryo-Slice and View on Thermo Scientific Helios 5 Hydra PFIB [477 micrographs in TIFF format] | Kelley R, Khavnekar S, Wietrzynski W, Plitzko J, Kotecha A | 4.4 GB | — | |
2021-09-22 | Closed linker DNA nucleosome reconstituted with GUB DNA [1320 multi-frame micrographs composed of 50 frames each in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] |
624.4 GB | 3.77 Å | |
2023-12-04 | Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric and asymmetric conformations [multiple data sets in MRC format] | Xu X, Ben-Hail D, des Georges A, Pozharski E [Pubmed: 31896582] [DOI: 10.1073/pnas.1919490117] |
704.4 GB | 2.8 - 3.1 Å | |
2018-08-16 | Combining high-resolution cryo-electron microscopy and mutagenesis to develop cowpea mosaic virus for bionanotechnology [5619 multi-frame micrographs composed of 1 frames each in MRC format] | Thompson RF, Iadanza MG, Hesketh EL, Rawson S, Ranson NA, Meshcheriakova Y, Durrant A, Lomonossoff GP [Pubmed: 30487656] [DOI: 10.1038/s41596-018-0084-8] |
351.5 GB | 2.7 Å | |
2021-03-19 | Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT [624 multi-frame micrographs composed of 40 frames each in TIFF format] | Komori Y, Nishida N, Takarada O, Watanabe A, Tamura S, Kubo S, Shimada I, Kikkawa M [Pubmed: 32098965] [DOI: 10.1038/s41467-020-14842-8] |
124.3 GB | 3.62 Å | |
2021-03-19 | Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT [1825 multi-frame micrographs composed of 40 frames each in TIFF format] | Komori Y, Nishida N, Takarada O, Watanabe A, Tamura S, Kubo S, Shimada I, Kikkawa M [Pubmed: 32098965] [DOI: 10.1038/s41467-020-14842-8] |
360.5 GB | 3.94 Å | |
2018-04-03 | Conformational Dynamics of human Bact spliceosome [multiple data sets in MRC format] | Haselbach D, Stark H [Pubmed: 29361316] [DOI: 10.1016/j.cell.2018.01.010] |
2.8 TB | 4.5 - 16.0 Å | |
2017-08-23 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle [stack of 117471 particles in MRCS format] | Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y [Pubmed: 28689658] [DOI: 10.1016/j.molcel.2017.06.007] |
70.0 GB | 4.5 - 8.9 Å | |
2022-05-17 | Conformational rearrangements upon start codon recognition in human 48S translation initiation complex [multiple data sets in MRC and MRCS formats] | Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N [Pubmed: 35489072] [DOI: 10.1093/nar/gkac283] |
1.1 TB | 3.7 - 4.7 Å | |
2020-10-02 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å [2087 multi-frame micrographs composed of 150 frames each in TIFF format] | Flores JA, Haddad BG, Dolan KA, Myers JB, Yoshioka CC, Copperman J, Zuckerman DM, Reichow SL [Pubmed: 32859914] [DOI: 10.1038/s41467-020-18120-5] |
4.1 TB | 1.94 - 2.5 Å | |
2018-05-02 | Correlative microscopy of vitreous sections provides insights into BAR-domain organisation in situ [9 tilt series in MRC format] | Bharat TAM, Hoffmann PC, Kukulski W [Pubmed: 29681471] [DOI: 10.1016/j.str.2018.03.015] |
27.9 GB | — |